发明授权
EP1234033B1 Methods for targeting cells that express fibroblast growth factor receptor-3 or-2
有权
方法,其是针对细胞中表达的成纤维细胞生长因子受体-3或-2
- 专利标题: Methods for targeting cells that express fibroblast growth factor receptor-3 or-2
- 专利标题(中): 方法,其是针对细胞中表达的成纤维细胞生长因子受体-3或-2
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申请号: EP00980829.6申请日: 2000-11-28
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公开(公告)号: EP1234033B1公开(公告)日: 2011-12-28
- 发明人: WEST, James, W.
- 申请人: ZymoGenetics, Inc.
- 申请人地址: 1201 Eastlake Avenue East Seattle, WA 98102 US
- 专利权人: ZymoGenetics, Inc.
- 当前专利权人: ZymoGenetics, Inc.
- 当前专利权人地址: 1201 Eastlake Avenue East Seattle, WA 98102 US
- 代理机构: MacLean, Martin Robert
- 优先权: US452977 19991202
- 国际公布: WO2001039788 20010607
- 主分类号: C12N15/12
- IPC分类号: C12N15/12 ; C07K14/50 ; C12N15/18 ; C12N15/62 ; A61K38/18
摘要:
Fibroblast growth factor-18 (FGF-18) binds with FGF receptors-2 and -3. Compositions comprising an FGF-18 component can be used to target cells that express these receptors. Suitable targets include tumor cells that express constitutively activated forms of FGF receptors-2 and -3.
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