发明公开
EP1235848A1 INDUCING CELLULAR IMMUNE RESPONSES TO CARCINOEMBRYONIC ANTIGEN USING PEPTIDE AND NUCLEIC ACID COMPOSITIONS
审中-公开
STIMULUSCULLÄRER免疫反应一个CARCINOEMBRYONEN抗原肽使用和核酸组合物
- 专利标题: INDUCING CELLULAR IMMUNE RESPONSES TO CARCINOEMBRYONIC ANTIGEN USING PEPTIDE AND NUCLEIC ACID COMPOSITIONS
- 专利标题(中): STIMULUSCULLÄRER免疫反应一个CARCINOEMBRYONEN抗原肽使用和核酸组合物
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申请号: EP00984204.8申请日: 2000-12-11
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公开(公告)号: EP1235848A1公开(公告)日: 2002-09-04
- 发明人: FIKES, John , SETTE, Alessandro , SIDNEY, John , SOUTHWOOD, Scott , CHESNUT, Robert , CELIS, Esteban , KEOGH, Elissa
- 申请人: Epimmune Inc.
- 申请人地址: 5820 Nancy Ridge Drive San Diego, CA 92121 US
- 专利权人: Epimmune Inc.
- 当前专利权人: Epimmune Inc.
- 当前专利权人地址: 5820 Nancy Ridge Drive San Diego, CA 92121 US
- 代理机构: Cripps, Joanna Elizabeth
- 优先权: US458302 19991210
- 国际公布: WO01042270 20010614
- 主分类号: C07H21/04
- IPC分类号: C07H21/04 ; C07H21/02 ; C07K4/12 ; C07K7/00 ; C07K9/00 ; C07K14/705 ; A61K38/04 ; A61K38/08 ; A61K38/10 ; A61K38/17
摘要:
This invention uses our knowledge of the mechanisms by which antigen is recognized by T cells to identify and prepare carcino-embryonic antigen (CEA) epitopes, and to develop epitope-based vaccines directed towards CEA-bearing tumors. More specifically, this application communicates our discovery of pharmaceutical compositions and methods of use in the prevention and treatment of cancer.
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