发明公开
EP1237564A1 INDUCING CELLULAR IMMUNE RESPONSES TO P53 USING PEPTIDE AND NUCLEIC ACID COMPOSITIONS
审中-公开
诱导的细胞免疫应答P53以肽和核酸化合物
- 专利标题： INDUCING CELLULAR IMMUNE RESPONSES TO P53 USING PEPTIDE AND NUCLEIC ACID COMPOSITIONS
- 专利标题（中）： 诱导的细胞免疫应答P53以肽和核酸化合物
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申请号： EP00984231.1申请日： 2000-12-11
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公开(公告)号： EP1237564A1公开(公告)日： 2002-09-11
- 发明人: FIKES, John , SETTE, Alessandro , SIDNEY, John , SOUTHWOOD, Scott , CHESNUT, Robert , CELIS, Esteban , KEOGH, Elissa
- 申请人： Epimmune, Inc.
- 申请人地址： Suite 100,5820 Nancy Ridge Drive San Diego,California 92121 US
- 专利权人： Epimmune, Inc.
- 当前专利权人： Epimmune, Inc.
- 当前专利权人地址： Suite 100,5820 Nancy Ridge Drive San Diego,California 92121 US
- 代理机构： Cripps, Joanna Elizabeth
- 优先权： US458297 19991210
- 国际公布： WO01041788 20010614
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; A61K38/03 ; A61K38/08 ; A61K38/16 ; A61K39/00 ; C07H21/00 ; C07K9/00 ; C07K14/00
摘要：
This invention uses our knowledge of the mechanisms by which antigen is recognized by T cells to identify and prepare p53 epitopes, and to develop epitope-based vaccines directed towards p53-bearing tumors. More specifically, this application communicates our discovery of pharmaceutical compositions and methods of use in the prevention and treatment of cancer.
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