There is provided a method of delivering a benefit agent to a selected area of a fabric for exerting a predetermined activity, wherein the area is pre-treated with a multi-specific binding molecule which has a high binding affinity to said area through one specificity and is capable of binding to said benefit agent through another specificity, followed by contacting said pre-treated area with said benefit agent, to enhance said pre-determined activity to said area. Preferably, the binding molecule is an antibody or fragment thereof, or a fusion protein comprising a cellulose binding domain and a domain having a high binding affinity to another ligand which is directed to said benefit agent. The method is useful for stain removal, perfume delivery, and treating collars and cuffs for wear. Also provided is a device for use in this method, which is a dispenser capable of depositing a multi-specific binding molecule to a selected area of a fabric through a semi-solid wax or soap-stick, spray, aerosol, impregnated brush, gel, or foam, and the like.