发明公开
- 专利标题： CURCUMIN ANALOGUES FOR TREATING CANCER
- 专利标题（中）： 姜黄素衍生物用于癌症治疗
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申请号： EP00982389.9申请日： 2000-12-04
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公开(公告)号： EP1242379A1公开(公告)日： 2002-09-25
- 发明人: SNYDER, James, P. , DAVIS, Matthew, C. , ADAMS, Brian , SHOJI, Mamoru , LIOTTA, Dennis, C. , FERSTL, Eva, M. , SUNAY, Ustun, B.
- 申请人： Emory University
- 申请人地址： 2009 Ridgewood Drive , Atlanta, Georgia 30322 US
- 专利权人： Emory University
- 当前专利权人： Emory University
- 当前专利权人地址： 2009 Ridgewood Drive , Atlanta, Georgia 30322 US
- 代理机构： Keen, Celia Mary
- 优先权： US168913P 19991203
- 国际公布： WO01040188 20010607
- 主分类号： C07D213/63
- IPC分类号： C07D213/63 ; A61P35/00 ; C07C49/235 ; C07C49/248 ; C07C317/10 ; C07C33/48 ; C07D451/02
摘要：
The present invention is directed to curcumin analogs (I), wherein Y is OH, halogen, or CF3; Z is H, OH, OR1, halogen, or CF3; X1 and X2 are independently C or N; and A is as defined in the application; exhibiting anti-tumor and anti-angiogenic properties, pharmaceutical formulations including such compounds and methods of using such compounds.
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