发明公开
EP1248792A4 ANTISENSE MODULATION OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA EXPRESSION
审中-公开
表达GAMMA过氧化物酶体增殖物激活受体的反义调节
- 专利标题： ANTISENSE MODULATION OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA EXPRESSION
- 专利标题（中）： 表达GAMMA过氧化物酶体增殖物激活受体的反义调节
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申请号： EP01942628申请日： 2001-01-11
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公开(公告)号： EP1248792A4公开(公告)日： 2004-11-17
- 发明人: MCKAY ROBERT , BORCHERS ALEXANDER H , BAKER BRENDA F
- 申请人： ISIS PHARMACEUTICALS INC
- 专利权人： ISIS PHARMACEUTICALS INC
- 当前专利权人： ISIS PHARMACEUTICALS INC
- 优先权： US48434500 2000-01-18
- 主分类号： C12N15/09
- IPC分类号： C12N15/09 ; A61K31/7115 ; A61K31/712 ; A61K31/7125 ; A61K38/00 ; A61K45/00 ; A61K48/00 ; A61P1/00 ; A61P3/10 ; A61P9/00 ; A61P29/00 ; A61P35/00 ; A61P43/00 ; C12N15/113 ; C07H21/02 ; C07H21/04 ; C12Q1/68
摘要：
Antisense compounds, compositions and methods are provided for modulating the expression of Peroxisome proliferator-activated receptor gamma. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding Peroxisome proliferator-activated receptor gamma. Methods of using these compounds for modulation of Peroxisome proliferator-activated receptor gamma expression and for treatment of diseases associated with expression of Peroxisome proliferator-activated receptor gamma are provided.
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