发明授权
- 专利标题： USE OF CYP52A2A PROMOTER TO INCREASE GENE EXPRESSION IN YEAST
- 专利标题（中）： 使用本CYP52A2A子来增加酵母基因表达
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申请号： EP01953603.6申请日： 2001-07-25
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公开(公告)号： EP1303593B1公开(公告)日： 2008-01-09
- 发明人: CRAFT, David, L. , WILSON, C., Ron , EIRICH, Dudley , ZHANG, Yeyan
- 申请人： Cognis IP Management GmbH
- 申请人地址： Henkelstrasse 67 40589 Düsseldorf DE
- 专利权人： Cognis IP Management GmbH
- 当前专利权人： Cognis IP Management GmbH
- 当前专利权人地址： Henkelstrasse 67 40589 Düsseldorf DE
- 代理机构： Fiesser, Gerold Michael
- 优先权： US220850P 20000726; US911781 20010724
- 国际公布： WO2002008412 20020131
- 主分类号： C12N15/00
- IPC分类号： C12N15/00
摘要：
A nucleic acid sequence including a CYP promoter operably linked to nucleic acid encoding a heterologous protein is provided to increase transcription of the nucleic acid. Expression vectors and host cells containing the nucleic acid sequence are also provided. The methods and compositions described herein are especially useful in the production of polycarboxylic acids by yeast cells.
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