Medicinal compositions, which quickly disintegrate after putting into the oral cavity and exert a hardness sufficient for the common production, distribution and utilization procedures, are prepared by adding, to sugar alcohols or sugars, sugar alcohols or sugars having lower melting points, and then subjecting the resultant mixture to compression and heating. Thus, medicinal compositions, which quickly disintegrate after putting into the oral cavity without resort to water and are excellent in handling properties because of having a hardness sufficient for the common production, distribution and utilization procedures, can be provided. Moreover, it is possible to provide a process for more conveniently producing a medicinal composition whereby the contact of a drug component with moisture can be avoided, if needed.