发明公开
EP1335021A1 GENOMES PARTICIPATING IN RHEUMATOID ARTHRITIS, METHOD OF THE DIAGNOSIS THEREOF, METHOD OF EVALUATING THE ONSET POSSIBILITY THEREOF, DIAGNOSTIC KIT FOR DETECTING THEM AND THERAPEUTIC METHOD AND REMEDIES FOR RHEUMATOID ARTHRITIS
审中-公开
类风湿性关节炎一个复杂的基因组中，诊断方法的一种用于评估OUTBREAK IT的可能性，诊断试剂盒，用于检测该基因的，治疗程序和补救措施为风湿性关节炎
- 专利标题： GENOMES PARTICIPATING IN RHEUMATOID ARTHRITIS, METHOD OF THE DIAGNOSIS THEREOF, METHOD OF EVALUATING THE ONSET POSSIBILITY THEREOF, DIAGNOSTIC KIT FOR DETECTING THEM AND THERAPEUTIC METHOD AND REMEDIES FOR RHEUMATOID ARTHRITIS
- 专利标题（中）： 类风湿性关节炎一个复杂的基因组中，诊断方法的一种用于评估OUTBREAK IT的可能性，诊断试剂盒，用于检测该基因的，治疗程序和补救措施为风湿性关节炎
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申请号： EP01978865.2申请日： 2001-10-24
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公开(公告)号： EP1335021A1公开(公告)日： 2003-08-13
- 发明人: SHIOZAWA, Shunichi , KONISHI, Yoshitake
- 申请人： Shiozawa, Shunichi
- 申请人地址： 11-6, Takenodai 2-chome, Nishiku Kobe-shi, Hyogo 651-2274 JP
- 专利权人： Shiozawa, Shunichi
- 当前专利权人： Shiozawa, Shunichi
- 当前专利权人地址： 11-6, Takenodai 2-chome, Nishiku Kobe-shi, Hyogo 651-2274 JP
- 代理机构： de Roquemaurel, Bruno
- 优先权： JP2000324296 20001024; JP2001090546 20010327; JP2001099990 20010330
- 国际公布： WO02034912 20020502
- 主分类号： C12N15/12
- IPC分类号： C12N15/12 ; C07K14/47 ; C12Q1/68 ; G01N33/50 ; A61K38/17 ; A61K48/00
摘要：
Mutations in a genome associating in rheumatoid arthritis (RA) are found in human DR3 genomic DNA having the base sequence represented by SEQ ID NO:1. The invention provides a genome having such mutations, transcripts thereof, a method of highly accurately evaluating the RA onset or the RA onset possibility by using the mutations thereof, an evaluation kit therefor, and a therapeutic method and remedies for RA.
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