发明公开
- 专利标题： SUBSTITUTED BENZOINDOLES AS SPLA2 INHIBITORS
- 专利标题（中）： 取代的苯并吲哚作为SPLA2抑制剂
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申请号： EP01986459.4申请日： 2001-12-06
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公开(公告)号： EP1349832A2公开(公告)日： 2003-10-08
- 发明人: BEIGHT, Douglas, Wade , KINNICK, Michael, Dean , LIN, Ho-Shen , MORIN, John, Michael, Junior , RICHETT, Michael, Enrico , SALL, Daniel, Jon , SAWYER, Jason, Scott , SMITH, Edward, C R
- 申请人： ELI LILLY AND COMPANY
- 申请人地址： Lilly Corporate Center Indianapolis, Indiana 46285 US
- 专利权人： ELI LILLY AND COMPANY
- 当前专利权人： ELI LILLY AND COMPANY
- 当前专利权人地址： Lilly Corporate Center Indianapolis, Indiana 46285 US
- 代理机构： Kingsbury, Oliver William
- 优先权： US256281P 20001218
- 国际公布： WO02050028 20020627
- 主分类号： C07D209/00
- IPC分类号： C07D209/00 ; A61K31/40 ; A61P29/00
摘要：
A novel class of benz[f]indole compounds see structure (I) is disclosed together with the use of such compounds for inhibiting sPLA2 mediated release of fatty acids for treatment of inflammatory diseases such as septic shock.
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