发明公开
EP1349840A2 ANILINOPYRIMIDINE DERIVATIVES AS JNK PATHWAY INHIBITORS AND COMPOSITIONS AND METHODS RELATED THERETO
有权
苯胺嘧啶衍生物作为“JNK通路抑制剂”组合物和相关技术
- 专利标题： ANILINOPYRIMIDINE DERIVATIVES AS JNK PATHWAY INHIBITORS AND COMPOSITIONS AND METHODS RELATED THERETO
- 专利标题（中）： 苯胺嘧啶衍生物作为“JNK通路抑制剂”组合物和相关技术
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申请号： EP01996103.6申请日： 2001-12-05
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公开(公告)号： EP1349840A2公开(公告)日： 2003-10-08
- 发明人: KOIS, Adam , MACFARLANE, Karen, J. , SATOH, Yoshitaka , BHAGWAT, Shripad, S. , PARNES, Jason, S. , PALANKI, Moorthy, S., S. , ERDMAN, Paul, E.
- 申请人： SIGNAL PHARMACEUTICALS, INC.
- 申请人地址： 5555 Oberlin Drive San Diego, CA 92121 US
- 专利权人： SIGNAL PHARMACEUTICALS, INC.
- 当前专利权人： SIGNAL PHARMACEUTICALS, INC.
- 当前专利权人地址： 5555 Oberlin Drive San Diego, CA 92121 US
- 代理机构： Jump, Timothy John Simon
- 优先权： US251904P 20001206
- 国际公布： WO02046170 20020613
- 主分类号： C07D239/00
- IPC分类号： C07D239/00
摘要：
Compounds having activity as inhibitors of the JNK pathway are disclosed. The compounds of this invention are anilinopyrimidine derivatives having the following structure: (I) wherein R1 through R6 are as defined herein. Such compounds have utility in the treatment of a wide range of conditions that are responsive to inhibition of the JNK pathway. Thus, methods of treating such conditions are also disclosed, as are pharmaceutical compositions containing one or more compounds of the above compounds.
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