发明公开
- 专利标题: ALKANOIC ACID DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE THEREOF
- 专利标题(中): 的烷酸衍生物,用于生产及其用途
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申请号: EP01272544申请日: 2001-12-28
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公开(公告)号: EP1357115A4公开(公告)日: 2004-04-07
- 发明人: MOMOSE YU , MAEKAWA TSUYOSHI , TAKAKURA NOBUYUKI , ODAKA HIROYUKI , KIMURA HIROYUKI , ITO TATSUYA
- 申请人: TAKEDA CHEMICAL INDUSTRIES LTD
- 专利权人: TAKEDA CHEMICAL INDUSTRIES LTD
- 当前专利权人: TAKEDA CHEMICAL INDUSTRIES LTD
- 优先权: JP2000402648 2000-12-28
- 主分类号: A61P3/06
- IPC分类号: A61P3/06 ; A61P3/10 ; A61P9/12 ; A61P13/12 ; A61P19/10 ; A61P27/02 ; A61P31/04 ; A61P43/00 ; C07D263/32 ; C07D277/24 ; C07D277/32 ; C07D277/34 ; C07D277/42 ; C07D403/04 ; C07D413/04 ; C07D413/06 ; C07D413/12 ; C07D413/14 ; C07D417/06 ; C07D417/12 ; C07D417/14
摘要:
Alkanoic acid derivatives represented by the general formula (I) or salts thereof, useful as preventive and/or therapeutic agents for diabetes, hyperlipidemia, impaired glucose tolerance, and so on: (I) wherein R1 is an optionally substituted five-membered aromatic heterocyclic group; X is a free valency or the like; Q is a divalent hydrocarbon group containing 1 to 20 carbon atoms; Y is a free valency or the like; A is an aromatic ring which may have one to three substituents; Z is -(CH¿2)n-Z?1- (wherein n is an integer of 1 to 8; and Z1 is oxygen or the like) or the like; B is an optionally mono- to tri-substituted pyridine ring or the like; U is a free valency or the like; W is a divalent hydrocarbon group containing 1 to 20 carbon atoms; and R3 is -OH or the like, with the proviso that when B is an optionally mono- to tri-substituted benzene ring, U is a free valency.
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