发明公开
- 专利标题： IMPROVED CONTROLLED RELEASE ORAL DOSAGE FORM
- 专利标题（中）： 改进的口服剂型缓释
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申请号： EP02723104.2申请日： 2002-02-08
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公开(公告)号： EP1357898A2公开(公告)日： 2003-11-05
- 发明人: LI, Boyong , CHEN, Chih-Ming , CHENG, Xiu Xiu , NANGIA, Avinash
- 申请人： ANDRX Pharmaceuticals, Inc.
- 申请人地址： 4955 Orange Drive Davie, FL 33314 US
- 专利权人： ANDRX Pharmaceuticals, Inc.
- 当前专利权人： ANDRX Pharmaceuticals, Inc.
- 当前专利权人地址： 4955 Orange Drive Davie, FL 33314 US
- 代理机构： Schupfner, Georg U.
- 优先权： US267456P 20010208; US267457P 20010208
- 国际公布： WO02062299 20020815
- 主分类号： A61K9/14
- IPC分类号： A61K9/14 ; A61K9/16 ; A01N33/02
摘要：
A once a day bupropion hydrochloride formulation comprising applying a bupropion/cellulose ether suspension to inert spheres wherein the spheres are further divided and coated with two types of film being, an enteric coating and a hydrophobic coating, wherein the active drug is then released at various pH throughout the gastrointestinal tract maintaining a therapeutic range over an extended period of time.
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