发明公开
EP1366167A2 MATERIEL BIOLOGIQUE POUR LA PREPARATION DE COMPOSITIONS PHARMACEUTIQUES DESTINEES AU TRAITEMENT DE MAMMIFERES
审中-公开
生物材料药物组合物的哺乳动物的治疗PRODUCTION
- 专利标题： MATERIEL BIOLOGIQUE POUR LA PREPARATION DE COMPOSITIONS PHARMACEUTIQUES DESTINEES AU TRAITEMENT DE MAMMIFERES
- 专利标题（英）： Biological organism for preparing pharmaceutical compositions for treating mammals
- 专利标题（中）： 生物材料药物组合物的哺乳动物的治疗PRODUCTION
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申请号： EP02701327.5申请日： 2002-01-28
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公开(公告)号： EP1366167A2公开(公告)日： 2003-12-03
- 发明人: PAUL, Stéphane , REGULIER, Etienne
- 申请人： TRANSGENE S.A.
- 申请人地址： 11, rue de Molsheim 67000 Strasbourg FR
- 专利权人： TRANSGENE S.A.
- 当前专利权人： TRANSGENE S.A.
- 当前专利权人地址： 11, rue de Molsheim 67000 Strasbourg FR
- 代理机构： Ahner, Francis
- 优先权： EP01440017 20010126
- 国际公布： WO02059291 20020801
- 主分类号： C12N15/13
- IPC分类号： C12N15/13
摘要：
The invention concerns a biological organism comprising at least: (i) a nucleic acid coding for all or part of an antibody, said antibody being expressed at the surface of a host cell and capable of being fixed to a polypeptide present at the surface of a cytotoxic effector cell or of a T-helper lymphocyte and involved in the process of activating such a cell and (ii) a nucleic acid coding for all or part of a polypeptide involved in the stimulation of an immune response or in attraction to the site of expression and activation of cytotoxic effector cells or of T-helper lymphocytes, said polypeptide being selected among chemokines and co-stimulation molecules. The invention also concerns a host cell and a pharmaceutical composition containing said biological organism and their therapeutic or prophylactic uses.
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