发明公开
EP1382690A1 Method to reduce false positive outcomes in prion assays
审中-公开
在Prionenassays，Verfahren zum Reduzieren von falsch-positiven Ergebnissen
- 专利标题： Method to reduce false positive outcomes in prion assays
- 专利标题（中）： 在Prionenassays，Verfahren zum Reduzieren von falsch-positiven Ergebnissen
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申请号： EP02077909.6申请日： 2002-07-17
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公开(公告)号： EP1382690A1公开(公告)日： 2004-01-21
- 发明人: van Oers, Josephus W. A. M. , van der Vorst, Teun J. K. , Hack, Cornelis E. , van Engelenburg, Franciscus A. C.
- 申请人： Stichting Sanquin Bloedvoorziening
- 申请人地址： Plesmanlaan 125 1066 CX Amsterdam NL
- 专利权人： Stichting Sanquin Bloedvoorziening
- 当前专利权人： Stichting Sanquin Bloedvoorziening
- 当前专利权人地址： Plesmanlaan 125 1066 CX Amsterdam NL
- 代理机构： Prins, Adrianus Willem
- 主分类号： C12Q1/37
- IPC分类号： C12Q1/37 ; G01N33/68
摘要：
This invention relates to the field of prion diseases. A method is provided to reduce false positive outcomes in a test by monitoring the activity of a proteolytic enzyme in a test sample comprising providing the test sample with a substrate and contacting the enzyme with said substrate to allow conversion of the substrate by the enzyme into a detectable product and detecting said product. Use of a method according to the invention can improve the reliability of prion tests.
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