发明公开
EP1384777A1 GENOMIC DNAS PARTICIPATING IN RHEUMATOID ARTHRITIS, METHOD OF DIAGNOSING THE SAME, METHOD OF JUDGING ONSET RIKS THEREOF AND DIAGNOSTIC KIT FOR DETECTING THE SAME
有权
风湿性关节炎相关的基因组DNA诊断程序应确保程序，以评估这种风险和诊断试剂盒的爆发为它的检测
- 专利标题： GENOMIC DNAS PARTICIPATING IN RHEUMATOID ARTHRITIS, METHOD OF DIAGNOSING THE SAME, METHOD OF JUDGING ONSET RIKS THEREOF AND DIAGNOSTIC KIT FOR DETECTING THE SAME
- 专利标题（中）： 风湿性关节炎相关的基因组DNA诊断程序应确保程序，以评估这种风险和诊断试剂盒的爆发为它的检测
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申请号： EP02713262.0申请日： 2002-03-29
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公开(公告)号： EP1384777A1公开(公告)日： 2004-01-28
- 发明人: SHIOZAWA, Shunichi , KOMAI, Koichiro , YAGI, Hirofumi , MATSUURA, Nao
- 申请人： Shiozawa, Shunichi
- 申请人地址： 11-6, Takenodai 2-chome, Nishiku Kobe-shi, Hyogo 651-2274 JP
- 专利权人： Shiozawa, Shunichi
- 当前专利权人： Shiozawa, Shunichi
- 当前专利权人地址： 11-6, Takenodai 2-chome, Nishiku Kobe-shi, Hyogo 651-2274 JP
- 代理机构： Owen, Deborah Jane
- 优先权： JP2001102006 20010330
- 国际公布： WO2002079466 20021010
- 主分类号： C12N15/09
- IPC分类号： C12N15/09 ; C12Q1/68 ; G01N33/566 ; G01N33/50
摘要：
A genomic DNA involved in rheumatoid arthritis, a method of diagnosing rheumatoid arthritis or a method of judging onset risk of rheumatoid arthritis, and a diagnostic kit for diagnosing rheumatoid arthritis or judging onset risk of rheumatoid arthritis, which genomic DNA comprises at least one of the following mutations in genomic DNA consisting of the base sequence of SEQ ID NO: 1:
(1) substitution of thymine (t) for cytosine (c) at the position-1987;
(2) substitution of guanine (g) for thymine (t) at the position-3664; and
(3) substitution of cytosine (c) for adenine (a) at the position-3769.
(1) substitution of thymine (t) for cytosine (c) at the position-1987;
(2) substitution of guanine (g) for thymine (t) at the position-3664; and
(3) substitution of cytosine (c) for adenine (a) at the position-3769.
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