发明公开
- 专利标题： DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES
- 专利标题（中）： 二肽基抑制剂对于糖尿病的治疗或预防
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申请号： EP02753819.8申请日： 2002-03-22
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公开(公告)号： EP1385508A1公开(公告)日： 2004-02-04
- 发明人: ASHTON, Wallace, T. , CALDWELL, Charles, G. , OK, Hyun , PARMEE, Emma, R. , WEBER, Ann, E.
- 申请人： Merck & Co., Inc.
- 申请人地址： 126 East Lincoln Avenue Rahway,New Jersey 07065-0907 US
- 专利权人： Merck & Co., Inc.
- 当前专利权人： Merck & Co., Inc.
- 当前专利权人地址： 126 East Lincoln Avenue Rahway,New Jersey 07065-0907 US
- 代理机构： Horgan, James Michael Frederic
- 优先权： US278931P 20010327
- 国际公布： WO2002076450 20021003
- 主分类号： A61K31/40
- IPC分类号： A61K31/40 ; A61K31/426 ; A61K31/427 ; A61K31/4178 ; A61K31/4436 ; A61K31/4535 ; C07D207/09 ; C07D207/16 ; C07D277/04 ; C07D277/06 ; C07D417/04 ; C07D417/12
摘要：
The present invention is directed to compounds which are inhibitors of the dipeptidyl peptidase-IV enzyme ('DP-IV inhibitors') and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
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