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公开(公告)号：EP4452245A1
公开(公告)日：2024-10-30
申请号：EP22840695.5
申请日：2022-12-20
发明人： DELBECK, Martina , HAHN, Michael
IPC分类号： A61K31/216 , A61K31/435 , A61K31/427 , A61K31/4427 , A61P11/00
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公开(公告)号：EP4446322A1
公开(公告)日：2024-10-16
申请号：EP23742865.1
申请日：2023-01-17
发明人： WANG, Tong , HAO, Yan , XU, Yudong , YU, Qiang , DING, Juping , WANG, Yongsheng , CHEN, Bin , ZHAO, Jiahong
IPC分类号： C07D471/04 , A61K31/427 , A61P19/02
摘要： The present application relates to the field of pharmaceutical chemistry, and specifically to cyclopropanecarboxamide-contaning compounds of formula (I) and application thereof. The cyclopropanecarboxamide-containing compounds have great medical value and market potential for autoimmune diseases and myeloproliferative neoplasm diseases.
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公开(公告)号：EP3704111B1
公开(公告)日：2024-10-09
申请号：EP18873309.1
申请日：2018-11-02
IPC分类号： C07D413/12 , A61K31/421 , A61K31/427 , A61K31/4439 , A61K31/501 , A61K31/506 , A61P35/02 , C07D263/32 , C07D263/34 , C07D417/12 , G01N33/48
CPC分类号： C07D413/14 , C07D401/12 , C07D413/12 , C07D417/12 , C07D263/32 , G01N33/57426 , G01N2800/5220130101 , A61P35/02 , C07D249/04
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公开(公告)号：EP4433476A1
公开(公告)日：2024-09-25
申请号：EP22830015.8
申请日：2022-11-16
发明人： CHEN, Helen, Y. , DONG, Shuzhi , HU, Zhiyong , SU, Jing , YU, Tao , ZHANG, Yong
IPC分类号： C07D417/14 , A61K31/427 , A61P31/04
CPC分类号： C07D417/14 , A61P31/04
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公开(公告)号：EP4400114A1
公开(公告)日：2024-07-17
申请号：EP22864771.5
申请日：2022-09-06
申请人： Kyoto University
IPC分类号： A61K39/00 , A61K45/00 , A61K45/06 , A61P35/00 , A61P37/04 , C07K7/06 , C12N15/11 , A61K38/03 , A61K31/427 , A61K31/52
CPC分类号： A61K31/427 , A61K31/52 , A61K38/03 , A61K39/00 , A61K45/00 , A61K45/06 , A61P35/00 , A61P37/04 , C07K7/06 , C12N15/11
摘要： Provided is a pharmaceutical composition that can improve tumor immunogenicity. The present disclosure relates to a pharmaceutical composition containing, as an active ingredient, a splicing-controlling compound that modulates the activity of serine/arginine-rich splicing factors (SRSFs).
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公开(公告)号：EP4385507A1
公开(公告)日：2024-06-19
申请号：EP22213139.3
申请日：2022-12-13
发明人： BEIJNEN, Jacob Hendrik , van EIJK, Maarten , HUITEMA, Alwin Dagmar Redmar , LOOS, Nancy Hélène Catharina , SCHINKEL, Alfred Hermanus
IPC分类号： A61K31/337 , A61K31/427 , A61P35/00
CPC分类号： A61K31/337 , A61K31/427 , A61P35/00 , A61K45/06
摘要： The current invention relates to a pharmaceutical composition comprising an effective amount of cabazitaxel, or a CYP3A inhibitor, for use in a combination treatment in the treatment of cancer in a patient. The combination treatment comprises administering the pharmaceutical composition and the CYP3A inhibitor, and the dose of the CYP3A inhibitor is equivalent to 40 to 120 mg ritonavir. The current invention also relates to method and kit for the combination treatment thereof.
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公开(公告)号：EP4380939A1
公开(公告)日：2024-06-12
申请号：EP22764330.1
申请日：2022-08-05
发明人： CZERWONKA, Dominika , KRZYWIK, Julia , SOBIERAJSKI, Tomasz , KLEJBOROWSKA, Greta , ULLRICH, Malgorzata , MOZGA, Witold , HUCZYNSKI, Adam , PILASZEK, Przemyslaw
IPC分类号： C07D493/20 , A61P35/00 , A61K31/35 , A61K31/422 , A61K31/427 , A61K31/4433
CPC分类号： C07D493/20 , A61P35/00
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公开(公告)号：EP3096756B1
公开(公告)日：2024-06-12
申请号：EP15702917.4
申请日：2015-01-21
IPC分类号： A61K31/427 , A61K31/519 , A61K31/4985 , A61P5/38
CPC分类号： A61K31/427 , A61K31/4985 , A61K31/519 , A61P5/38
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公开(公告)号：EP4376840A1
公开(公告)日：2024-06-05
申请号：EP22850281.1
申请日：2022-07-27
申请人： Nura Bio, Inc.
发明人： KOLLURI, Rao , TEGLEY, Christopher Michael , ZHU, Liusheng , BROWN, Sean Pomeroy , TASKER, Andrew Stewart , GRICE, Cheryl A. , REYNOLDS, Charles Howard
IPC分类号： A61K31/44 , A01N43/78 , A61K31/4164 , A61K31/426 , A61K31/427 , A61K31/4409 , C07D213/16
CPC分类号： C07D401/06 , C07D417/14 , C07D417/06 , A61K45/06
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10.发明公开
公开(公告)号：EP4373520A1
公开(公告)日：2024-05-29
申请号：EP22845545.7
申请日：2022-07-21
IPC分类号： A61K39/215 , A61K39/39 , A61K31/4706 , A61K31/635 , A61K31/519 , A61K38/21 , A61K31/427 , A61K31/675 , A61K31/53 , A61K39/00
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