发明公开
EP1385522A2 COMBINATION COMPRISING A SIGNAL TRANSDUCTION INHIBITOR AND AN EPOTHILONE DERIVATIVE
有权
组合中包含信号传导和A抑制剂的埃坡霉素衍生物
- 专利标题: COMBINATION COMPRISING A SIGNAL TRANSDUCTION INHIBITOR AND AN EPOTHILONE DERIVATIVE
- 专利标题(中): 组合中包含信号传导和A抑制剂的埃坡霉素衍生物
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申请号: EP02744903.2申请日: 2002-02-26
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公开(公告)号: EP1385522A2公开(公告)日: 2004-02-04
- 发明人: BUCHDUNGER, Elisabeth , HELDIN, Carl-Henrik , ÖSTMAN, Arne , PIETRAS, Kristian , O'REILLY, Terence , ROTHERMEL, John, David , TRAXLER, Peter , WARTMANN, Markus , BRANDT, Ralf
- 申请人: Novartis AG , Novartis Pharma GmbH
- 申请人地址: Lichtstrasse 35 4056 Basel CH
- 专利权人: Novartis AG,Novartis Pharma GmbH
- 当前专利权人: Novartis AG,Novartis Pharma GmbH
- 当前专利权人地址: Lichtstrasse 35 4056 Basel CH
- 代理机构: Grubb, Philip William
- 优先权: GB0104840 20010227; US339040P 20011030
- 国际公布: WO2002067941 20020906
- 主分类号: A61K31/505
- IPC分类号: A61K31/505 ; A61K45/06 ; A61K31/425 ; A61P35/00
摘要:
The present invention relates to a combination comprising N-{5-[4-(4-methyl-piperazino-methyl) -benzoylamido]-2-methylphenyl}-4-(3-pyridyl)-2-pyrimidine-amine and an epothiione derivative; pharmaceutical composition comprising said combination; method of treatment comprising said combination; and commercial packages comprising said combination.
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