发明公开
EP1385984A2 COMPOUNDS DISPLAYED ON ICOSAHEDRAL PHAGE AND METHODS OF USING SAME
审中-公开
关于使用一个二十面体噬菌体PRESENTED连接和方法
- 专利标题： COMPOUNDS DISPLAYED ON ICOSAHEDRAL PHAGE AND METHODS OF USING SAME
- 专利标题（中）： 关于使用一个二十面体噬菌体PRESENTED连接和方法
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申请号： EP02728558.4申请日： 2002-03-21
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公开(公告)号： EP1385984A2公开(公告)日： 2004-02-04
- 发明人: BARRETT, Ronald, W. , DOWER, William, J. , GALLOP, Mark , WOIWODE, Thomas, F. , CWIRLA, Steven, E.
- 申请人： Xenoport, Inc.
- 申请人地址： 3410 Central Expressway Santa Clara, CA 95051 US
- 专利权人： Xenoport, Inc.
- 当前专利权人： Xenoport, Inc.
- 当前专利权人地址： 3410 Central Expressway Santa Clara, CA 95051 US
- 代理机构： Smart, Peter John
- 优先权： US277537P 20010321
- 国际公布： WO2002077182 20021003
- 主分类号： C12Q1/00
- IPC分类号： C12Q1/00 ; C12Q1/70 ; C12Q1/68 ; G01N33/53 ; G01N33/543 ; C12N7/00 ; C12N15/00 ; C12N15/09 ; C12N15/63 ; C12N15/70 ; C12N15/74 ; A61K38/00
摘要：
Icosahedral phage and collections thereof that display various compounds are provided. In some instances, the icosahedral phage include nucleic acid tags that serve to record a characteristic of the compound or compounds that are attached to the phage. A number of different methods for using the icosahedral phage to screen a library of compounds for a desired biological activity are also provided, especially assays for compounds that are substrates for receptor-mediated transport processes such as endocytosis and transcytosis.
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