发明公开
- 专利标题: DELIVERY OF ERECTILE DYSFUNCTION DRUGS THROUGH AN INHALATION ROUTE
- 专利标题(中): 药物的勃起问题通过吸入治疗管理
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申请号: EP02737132.7申请日: 2002-05-22
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公开(公告)号: EP1392259A2公开(公告)日: 2004-03-03
- 发明人: RABINOWITZ, Joshua, D. , ZAFFARONI, Alejandro, C.
- 申请人: Alexza Molecular Delivery Corporation
- 申请人地址: 1001 E. Meadow Circle Palo Alto, CA 94303 US
- 专利权人: Alexza Molecular Delivery Corporation
- 当前专利权人: Alexza Molecular Delivery Corporation
- 当前专利权人地址: 1001 E. Meadow Circle Palo Alto, CA 94303 US
- 代理机构: Thomson, Paul Anthony
- 优先权: US294203P 20010524; US317479P 20010905
- 国际公布: WO2002094219 20021128
- 主分类号: A61K9/72
- IPC分类号: A61K9/72
摘要:
The present invention relates to the delivery of sedative-hypnotics through an inhalation route. Specifically, it relates to aerosols containing sedative-hypnotics that are used in inhalation therapy. In a composition aspect of the present invention, the aerosol comprises particles comprising at least 5 percent by weight of a sedative-hypnotic. In a method aspect of the present invention, a sedative-hypnotic is delivered to a mammal through an inhalation route. The method comprises: a) heating a composition, wherein the composition comprises at least 5 percent by weight of a sedative-hypnotic, to form a vapor; and, b) allowing the vapor to cool, thereby forming a condensation aerosol comprising particles, which is inhaled by the mammal. In a kit aspect of the present invention, a kit for delivering a sedative-hypnotic through an inhalation route to a mammal is provided which comprises: a) a composition comprising at least 5 percent by weight of a sedative-hypnotic; and, b) a device that forms a sedative-hypnotic containing aerosol from the composition, for inhalation by the mammal.
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