The present invention relates to a method and a heavy metal, such as noble metal. E.g. gold, for implantation in vivo or in vitro in local areas in humans or animals, the gold is provided with a large surface to ensure ample release of gold ions. The heavy metal e.g. gold may be admixed to solids, (tablets, powders) liquids (solutions, lung sprays, eye drops, nose spray) or cremes, depending on how it is going to be used, on the different external or internal epithelial surfaces. Form implantation in tissues including the brain, the gold is provided as pieces of gold having a mass and surface adapted to the purpose, where the surface of the piece of gold is larger than a cylindrical piece of gold having the same mass. In a preferred embodiment, the pieces of gold are wound as springs.