发明公开
- 专利标题: NOVEL PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS
- 专利标题(中): 新吡咯作为药剂
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申请号: EP02744115.3申请日: 2002-05-13
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公开(公告)号: EP1397364A1公开(公告)日: 2004-03-17
- 发明人: SAWYER, Jason, Scott , BEIGHT, Douglas, Wade , CIAPETTI, Paola , DECOLLO, Todd, Vincent , GODFREY, Alexander, Glenn , GOODSON, Theodore, Jr. , HERRON, David, Kent , LI, Hong-Yu , LIAO, Junkai , MCMILLEN, William, Thomas , MILLER, Shawn, Christopher , MORT, Nicolas, Anthony , YINGLING, Jonathan, Michael , SMITH, Edward, C., R.
- 申请人: ELI LILLY AND COMPANY
- 申请人地址: Lilly Corporate Center Indianapolis, Indiana 46285 US
- 专利权人: ELI LILLY AND COMPANY
- 当前专利权人: ELI LILLY AND COMPANY
- 当前专利权人地址: Lilly Corporate Center Indianapolis, Indiana 46285 US
- 代理机构: Burnside, Ivan John
- 优先权: US293464P 20010524
- 国际公布: WO2002094833 20021128
- 主分类号: C07D487/04
- IPC分类号: C07D487/04 ; C07D498/04 ; C07D471/04 ; A61P7/04 ; A61P25/28 ; A61P31/00 ; A61P43/00 ; A61K31/33 ; A61K31/41 ; A61K31/535
摘要:
Novel pyrrazole derivative compounds and their use as pharmaceutical agents, in particular their use as TGF-beta signal transduction inhibitors. The disclosed invention relates to compounds of the structure (I) wherein (I) is a four, five, or six membered saturated ring and X is C, O or S.
公开/授权文献
- EP1397364B1 NOVEL PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS 公开/授权日:2007-07-25
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