发明公开
EP1405919A1 A method for electronically monitoring and recording cell cultures
失效
维尔法赫恩zur elektronischenÜberwachungund Aufzeichnung von Zellkulturen
- 专利标题: A method for electronically monitoring and recording cell cultures
- 专利标题(中): 维尔法赫恩zur elektronischenÜberwachungund Aufzeichnung von Zellkulturen
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申请号: EP03025616.8申请日: 1992-07-29
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公开(公告)号: EP1405919A1公开(公告)日: 2004-04-07
- 发明人: The designation of the inventor has not yet been filed
- 申请人: CELLSTAT TECHNOLOGIES, INC.
- 申请人地址: 755 Page Mill Road, Suite B6 Palo Alto, CA 94304 US
- 专利权人: CELLSTAT TECHNOLOGIES, INC.
- 当前专利权人: CELLSTAT TECHNOLOGIES, INC.
- 当前专利权人地址: 755 Page Mill Road, Suite B6 Palo Alto, CA 94304 US
- 代理机构: VOSSIUS & PARTNER
- 主分类号: C12Q1/08
- IPC分类号: C12Q1/08 ; G01N27/02
摘要:
This invention provides an improved system for monitoring and recording cell cultures. An improved lid (10) for the system includes pin sockets (28) interposed between traces (24) on a printed circuit board (22) and elongated, electrically conductive pins (38). A method for measuring a delay period for an alternating current voltage applied across a pair of pins (38) improves the stability of measurements made with the improved system. A method for applying a voltage across a pair of pins (38) which avoids exceeding a pre-established voltage avoids the possibility of damaging and/or destroying cells while monitoring their culture. Subtracting electrical conductivity measured for a reference well (16) that holds only cell growth media without cells from the electrical conductivity measured for other wells (16) during analysis of recorded data improves the presentation of test results obtained by monitoring and recording cell cultures.
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