发明公开
EP1432409A1 GRANULAT ODER PULVER ZUR HERSTELLUNG VON ÜBERZUGS- UND BINDEMITTELN F R ARZNEIFORMEN 有权
颗粒或粉末FOR为药物形式PRODUCING涂层和结合剂

  • 专利标题: GRANULAT ODER PULVER ZUR HERSTELLUNG VON ÜBERZUGS- UND BINDEMITTELN F R ARZNEIFORMEN
  • 专利标题(英): Granulate or powder for producing coating or binding agents for medicaments
  • 专利标题(中): 颗粒或粉末FOR为药物形式PRODUCING涂层和结合剂
  • 申请号: EP03790791.2
    申请日: 2003-07-08
  • 公开(公告)号: EP1432409A1
    公开(公告)日: 2004-06-30
  • 发明人: PETEREIT, Hans-UlrichMEIER, ChristianROTH, ErnaGRYCZKE, Andreas
  • 申请人: Röhm GmbH & Co. KG
  • 申请人地址: Kirschenallee 64293 Darmstadt DE
  • 专利权人: Röhm GmbH & Co. KG
  • 当前专利权人: Röhm GmbH & Co. KG
  • 当前专利权人地址: Kirschenallee 64293 Darmstadt DE
  • 优先权: DE10239999 20020827
  • 国际公布: WO2004019918 20040311
  • 主分类号: A61K9/28
  • IPC分类号: A61K9/28 A61K9/50 A61K9/16
GRANULAT ODER PULVER ZUR HERSTELLUNG VON ÜBERZUGS- UND BINDEMITTELN F R ARZNEIFORMEN
摘要:
The invention relates to a method for producing a granulate or powder which is suitable as a coating and binding agent for oral and dermal medicaments, cosmetic products or food supplements and substantially consists of (a) a copolymer containing radically polymerized C1 to C4 esters of acrylic acid or methacrylic acid and additional (meth)acrylate monomers that comprise functional tertiary amino groups, (b) 3 to 25 percent by weight relative to (a) of an emulsifier having an HLB value of at least 14, and (c) 5 to 50 percent by weight relative to (a) of C12 to C18 monocarboxylic acid or a C12 to C18 hydroxyl compound. Components (a), (b), and (c) are simultaneously or successively blended or mixed by optionally adding a pharmaceutical agent and/or other common loading agents, melted and mixed in a heatable mixer, whereupon the melted product is cooled and comminuted into a granulate or powder.
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