利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

17 条记录 (耗时 0.022 秒)

    MAKROPORÖSES KUNSTSTOFFPERLENMATERIAL
    2.
    发明公开
    MAKROPORÖSES KUNSTSTOFFPERLENMATERIAL 审中-公开
    万家乐孔塑料制成珠

    公开(公告)号：EP1556427A2

    公开(公告)日：2005-07-27

    申请号：EP03750435.4

    申请日：2003-08-25

    申请人： Röhm GmbH & Co. KG

    发明人： MENZLER, Stefan ,  PETEREIT, Hans-Ulrich ,  MEIER, Christian ,  BOLLER, Thomas ,  SÜFKE, Thomas ,  SCHULTES, Klaus ,  RECKTENWALD, Roger

    IPC分类号： C08F246/00 ,  C08F220/28 ,  C12N11/08

    CPC分类号： C08F220/28 ,  C08F246/00 ,  Y10S530/815

    摘要： The invention concerns a macroporous material in the form of plastic pearls, having an average particle diameter ranging between 10 and 1000 νm, containing a copolymer consisting of: a) 5 to 60 wt. % of monomers capable of being subjected to vinyl polymerization, being at least 1 % water soluble at 20 °C; b) 1 to 40 wt. % of monomers capable of being subjected to vinyl polymerization, comprising an additional functional group capable of being covalently bound to nucleophilic groups of ligands, during a polymerization-like reaction; c) 10 to 40 wt. % of hydrophilic monomers capable of being subjected to a crosslinking free radical polymerization, comprising at least two ethylenically unsaturated polymerisable groups; and d) 10 to 60 wt. % of monomers capable of the subjected to vinyl polymerization, not more than 1 % water soluble at 20 °C, the sum of the monomers a) through d) being generally equal to 100 %.

    AZNEIFORM UND VERFAHREN IHRER HERSTELLUNG
    9.
    发明公开
    AZNEIFORM UND VERFAHREN IHRER HERSTELLUNG 有权
    药物剂型及其制备方法

    公开(公告)号：EP1478352A1

    公开(公告)日：2004-11-24

    申请号：EP03711870.0

    申请日：2003-01-30

    申请人： Röhm GmbH & Co. KG

    发明人： PETEREIT, Hans-Ulrich ,  SÜFKE, Thomas ,  MEIER, Christian ,  SCHNABEL, Michael ,  BLESING, Ingrid ,  GRIMM, Stefan

    IPC分类号： A61K9/32 ,  A61K9/52 ,  C08F220/18

    CPC分类号： A61K9/5026 ,  A61K9/2846 ,  Y02A50/473

    摘要： The invention relates to a method for producing a pharmaceutical dosage form as tablets, pellets and/or in the form of an active ingredient-containing matrix, whereby the tablets, pellets and/or active ingredient-containing matrix contain a pharmaceutical active ingredient and a copolymer serving as a coating agent and/or binding agent, and optionally contain a core and pharmaceutically common additives. According to the invention, the copolymer, the pharmaceutical active ingredient, the optionally present core and/or the pharmaceutically common additives are processed using known techniques by melting, injection molding, extrusion, wet granulation, casting, dipping, spreading out, spraying on, or pressing to form tablets, pellets and/or an active ingredient-containing matrix. The inventive method is characterized in that a copolymer is used that consists of 20 to 34 wt. % methacrylic acid, 20 to 69 wt. % methylacrylate and 0 to 40 wt. % ethylacrylate and, optionally, of 0 to 10 wt. % of additional vinylically copolymerizable monomers with the provision that the glass transition temperature of the copolymer is no higher than 60° C according to ISO 11357-2, Item 3.3.3. The invention also relates to the pharmaceutical dosage form produced according to this method, said copolymer and the use thereof.