发明公开
- 专利标题: ANTISENSE MODULATION OF NAC EXPRESSION
- 专利标题(中): 抗神经调节DER NAC表达
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申请号: EP02766307.9申请日: 2002-09-19
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公开(公告)号: EP1436307A1公开(公告)日: 2004-07-14
- 发明人: BENNETT, C., Frank , FREIER, Susan, M.
- 申请人: ISIS PHARMACEUTICALS, INC.
- 申请人地址: 2292 Faraday Avenue Carlsbad, CA 92008 US
- 专利权人: ISIS PHARMACEUTICALS, INC.
- 当前专利权人: ISIS PHARMACEUTICALS, INC.
- 当前专利权人地址: 2292 Faraday Avenue Carlsbad, CA 92008 US
- 代理机构: Hallybone, Huw George
- 优先权: US956712 20010919
- 国际公布: WO2003024988 20030327
- 主分类号: C07H21/02
- IPC分类号: C07H21/02 ; C07H21/04 ; C12Q1/68 ; A61K48/00 ; C12N15/85 ; C12N15/86 ; C12P19/34
摘要:
Antisense compounds, compositions and methods are provided for modulating the expression of NAC. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding NAC. Methods of using these compounds for modulation of NAC expression and for treatment of diseases associated with expression of NAC are provided.
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