发明公开
- 专利标题： METHOD OF SEPARATING COMPOUND(S) FROM MIXTURE(S)
- 专利标题（中）： 方法分离的一个或多个的一种或多种混合物化合物
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申请号： EP02804426.1申请日： 2002-11-19
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公开(公告)号： EP1450925A1公开(公告)日： 2004-09-01
- 发明人: GANDELHEID, Thierry , LOPES, Anibal , FAYSON, James, Edward, Jr.
- 申请人： Scynexis, Inc.
- 申请人地址： 3501-C Tricenter Boulevard Durham, NC 27713 US
- 专利权人： Scynexis, Inc.
- 当前专利权人： Scynexis, Inc.
- 当前专利权人地址： 3501-C Tricenter Boulevard Durham, NC 27713 US
- 代理机构： Poulin, Gérard
- 优先权： US998137 20011203
- 国际公布： WO2003047717 20030612
- 主分类号： B01D15/08
- IPC分类号： B01D15/08
摘要：
The invention relates to methods of separating compounds of interest from mixtures using high performance liquid chromatography (HPLC). An initial separation of a sample of a mixture is performed to predict a retention time and elution time for the compound of interest on a preparative scale HPLC column and, optionally, to verify that an expected compound of interest is present in the mixture. Preparative scale HPLC is then used to separate and collect at least a portion of the compound from the mixture using the predicted elution time of the compound.
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