发明授权
- 专利标题: XANTHINE OXIDASE INHIBITORS
- 专利标题(中): XANTHINOXIDASEINHIBITOREN
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申请号: EP02780099.4申请日: 2002-11-14
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公开(公告)号: EP1452528B1公开(公告)日: 2008-08-13
- 发明人: YOSHIDA, Shinichi , TENDO, Atsushi , KOBAYASHI, Kunio , MOCHIDUKI, Nobutaka , YAMAKAWA, Tomio , SHINOHARA, Yoriko
- 申请人: NIPPON CHEMIPHAR CO., LTD.
- 申请人地址: 2-3, Iwamoto-cho 2-chome, Chiyoda-ku Tokyo 101-8678 JP
- 专利权人: NIPPON CHEMIPHAR CO., LTD.
- 当前专利权人: NIPPON CHEMIPHAR CO., LTD.
- 当前专利权人地址: 2-3, Iwamoto-cho 2-chome, Chiyoda-ku Tokyo 101-8678 JP
- 代理机构: Albrecht, Thomas
- 优先权: JP2001352340 20011116
- 国际公布: WO2003042185 20030522
- 主分类号: C07D235/18
- IPC分类号: C07D235/18 ; C07D263/56 ; C07D277/66 ; C07D471/04 ; C07D473/30 ; C07D473/34 ; C07D473/40 ; C07D498/04 ; A61K31/4184 ; A61K31/423 ; A61K31/428 ; A61P9/00
摘要:
Compounds represented by the general formula (I), and xanthine oxidase inhibitors containing the same as the active ingredient: (I) wherein R1 is OR4 or the like (wherein R4 is optionally substituted C1-8 alkyl or the like); R2 is halogeno, nitro, cyano, carboxyl, or the like; R3 is hydrogen, halogeno, hydroxyl, amino, carboxyl, or the like; X is NR11, oxygen, or sulfur (wherein R11 is hydrogen or optionally substituted C1-8 alkyl); and Y and Z are each CR12 or nitrogen (wherein R12 is the same as defined for R3).
公开/授权文献
- EP1452528A1 XANTHINE OXIDASE INHIBITORS 公开/授权日:2004-09-01
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