发明公开
- 专利标题： METHOD FOR TREATING OCULAR HYPERTENSION
- 专利标题（中）： 法高眼压症的治疗
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申请号： EP02784630.2申请日： 2002-11-27
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公开(公告)号： EP1461026A2公开(公告)日： 2004-09-29
- 发明人: OGIDIGBEN, Miller, J. , YOUNG, Robert, N. , METTERS, Kathleen, M. , SLIPETZ, Deborah, M. , BILLOT, Xavier
- 申请人： Merck & Co., Inc. , MERCK FROSST CANADA INC.
- 申请人地址： 126 East Lincoln Avenue Rahway,New Jersey 07065-0907 US
- 专利权人： Merck & Co., Inc.,MERCK FROSST CANADA INC.
- 当前专利权人： Merck & Co., Inc.,MERCK FROSST CANADA INC.
- 当前专利权人地址： 126 East Lincoln Avenue Rahway,New Jersey 07065-0907 US
- 代理机构： Buchan, Gavin MacNicol
- 优先权： US338117P 20011203; US400504P 20020802
- 国际公布： WO2003047513 20030612
- 主分类号： A61K31/16
- IPC分类号： A61K31/16 ; A61K31/40 ; A61K31/41 ; A61K31/215
摘要：
This invention relates to potent selective agonists of the EP4 subtype of prostaglandin E2 receptors, their use or a formulation thereof in the treatment of glaucoma and other conditions that are related to elevated intraocular pressure in the eye of a patient. This invention also relates to the use of such compounds to provide a neuroprotective effect to the eye of mammalian species, particularly humans.
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