发明公开
- 专利标题: CATHEPSIN CYSTEINE PROTEASE INHIBITORS
- 专利标题(中): 组织蛋白酶半胱氨酸蛋白酶抑制剂
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申请号: EP03716238.5申请日: 2003-02-28
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公开(公告)号: EP1482924A2公开(公告)日: 2004-12-08
- 发明人: BAYLY, Christopher, I. , BLACK, Cameron , LEGER, Serge , LI, Chun Sing , MCKAY, Dan , MELLON, Christophe , GAUTHIER, Jacques Yves , LAU, Cheuk , THERIEN, Michel , TRUONG, Vouy-Linh , GREEN, Michael, J. , HIRSCHBEIN, Bernard, L. , JANC, James, W. , PALMER, James, T. , BASKARAN, Chitra
- 申请人: MERCK FROSST CANADA INC. , AXYS PHARMACEUTICALS, INC.
- 申请人地址: 16711 Trans-Canada Highway Kirkland,Quebec H9H 3L1 CA
- 专利权人: MERCK FROSST CANADA INC.,AXYS PHARMACEUTICALS, INC.
- 当前专利权人: MERCK FROSST CANADA INC.,AXYS PHARMACEUTICALS, INC.
- 当前专利权人地址: 16711 Trans-Canada Highway Kirkland,Quebec H9H 3L1 CA
- 代理机构: Buchan, Gavin MacNicol
- 优先权: US361818P 20020305; US408704P 20020906
- 国际公布: WO2003075836 20030918
- 主分类号: A61K31/275
- IPC分类号: A61K31/275
摘要:
This invention relates to a novel class of compounds which are cysteine protease inhibitors, including but not limited to, inhibitors of cathepsins K, L, S and B. These compounds are useful for treating diseases in which inhibition of bone resorption is indicated, such as osteoporosis.
公开/授权文献
- EP1482924B1 CATHEPSIN CYSTEINE PROTEASE INHIBITORS 公开/授权日:2008-05-21
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