发明授权
EP1487428B1 AMINO-SUBSTITUTED (E)-2,6-DIALKOXYSTYRYL 4-SUBSTITUTED BENZYLSULFONES FOR TREATING PROLIFERATIVE DISORDERS
有权
氨基 - 取代的（E）-2,6-二DIALKOXYSTYRYL 4-取代BENZYLSULFONE用于治疗增殖性疾病
- 专利标题： AMINO-SUBSTITUTED (E)-2,6-DIALKOXYSTYRYL 4-SUBSTITUTED BENZYLSULFONES FOR TREATING PROLIFERATIVE DISORDERS
- 专利标题（中）： 氨基 - 取代的（E）-2,6-二DIALKOXYSTYRYL 4-取代BENZYLSULFONE用于治疗增殖性疾病
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申请号： EP03711347.9申请日： 2003-02-28
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公开(公告)号： EP1487428B1公开(公告)日： 2011-09-21
- 发明人: REDDY, Premkumar, E. , REDDY, Ramana, M., V. , BELL, Stanley, C.
- 申请人： Temple University - Of The Commonwealth System of Higher Education , Onconova Therapeutics, Inc.
- 申请人地址： Broad Street and Montgomery Avenue Philadelphia, PA 19122 US
- 专利权人： Temple University - Of The Commonwealth System of Higher Education,Onconova Therapeutics, Inc.
- 当前专利权人： Temple University - Of The Commonwealth System of Higher Education,Onconova Therapeutics, Inc.
- 当前专利权人地址： Broad Street and Montgomery Avenue Philadelphia, PA 19122 US
- 代理机构： Ouzman, Beverley Nicola Claire
- 优先权： US360697P 20020228
- 国际公布： WO2003072062 20030904
- 主分类号： A61K31/136
- IPC分类号： A61K31/136 ; C07C217/54 ; C07C251/08 ; C07C251/24
摘要：
Compounds useful as antiproliferative agents, including, for example, anticancer agents, are provided according to formula (I); wherein: X, X1, X2, Ra, R1, R2, R3, R4, R5, R6, R7, g, M, y, a, b, d, e, V, W, Z and Q are as defined herein.
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