发明公开
- 专利标题： STABILIZATION OF HYPOXIA INDUCIBLE FACTOR (HIF) ALPHA
- 专利标题（中）： 稳定价格缺氧诱导因子（HIF）ALPHA
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申请号： EP02797195.1申请日： 2002-12-06
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公开(公告)号： EP1487472A2公开(公告)日： 2004-12-22
- 发明人: GUENZLER-PUKALL, Volkmar , NEFF, Thomas, B. , WANG, Qingjian , AREND, Michael P. , FLIPPIN, Lee, A.
- 申请人： FIBROGEN, INC.
- 申请人地址： 260 Littlefield Drive South San Francisco, CA 94080 US
- 专利权人： FIBROGEN, INC.
- 当前专利权人： FIBROGEN, INC.
- 当前专利权人地址： 260 Littlefield Drive South San Francisco, CA 94080 US
- 代理机构： Goodfellow, Hugh Robin
- 优先权： US337082P 20011206; US349659P 20020116; US359683P 20020225; US386488P 20020605
- 国际公布： WO2003049686 20030619
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; C12N15/09 ; C12Q1/56 ; C12Q1/34
摘要：
The present invention relates to methods of stabilizing the alpha subunit of hypoxia inducible factor (HIF). The invention further relates to methods of preventing, pretreating, or treating conditions associated with HIF, including ischemic and hypoxic conditions. Compounds for use in these methods are also provided.
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