发明公开
EP1490317A1 GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF
审中-公开
糖皮质激素模拟物，用于生产含有它们的药物组合物，并且使用
- 专利标题： GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF
- 专利标题（中）： 糖皮质激素模拟物，用于生产含有它们的药物组合物，并且使用
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申请号： EP03723790.6申请日： 2003-03-21
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公开(公告)号： EP1490317A1公开(公告)日： 2004-12-29
- 发明人: BEKKALI, Y.,Boehringer Ingelheim Pharm., Inc. , CARDOZO, Mario, G. , KIRRANE, T. M.,Boehringer Ingelheim Pharm., Inc. , KUZMICH, D.,Boehringer Ingelheim Pharm., Inc. , PROUDFOOT, J.R.,Boehringer Ingelheim Pharm., Inc. , TAKAHASHI, H.,Boehringer Ingelheim Pharm., Inc. , THOMSON, D.,Boehringer Ingelheim Pharm., Inc. , WANG, J.,Boehringer Ingelheim Pharm., Inc. , ZINDELL, R.,Boehringer Ingelheim Pharm., Inc. , HARCKEN,C.H.J.J.,Boehringer Ingelheim Pharm., Inc. , RAZAVI, H.,Boehringer Ingelheim Pharm., Inc.
- 申请人： BOEHRINGER INGELHEIM PHARMACEUTICALS INC.
- 申请人地址： 900 Ridgebury Road,P.O. Box 368 Ridgefield,Connecticut 06877-0368 US
- 专利权人： BOEHRINGER INGELHEIM PHARMACEUTICALS INC.
- 当前专利权人： BOEHRINGER INGELHEIM PHARMACEUTICALS INC.
- 当前专利权人地址： 900 Ridgebury Road,P.O. Box 368 Ridgefield,Connecticut 06877-0368 US
- 代理机构： Hammann, Heinz, Dr.
- 优先权： US367801P 20020326
- 国际公布： WO2003082787 20031009
- 主分类号： C07C43/23
- IPC分类号： C07C43/23 ; A61K31/085 ; A61P29/00 ; A61P27/14 ; C07C255/54 ; C07C233/65 ; C07D307/79 ; C07D213/30
摘要：
Compounds of Formula (IA) and Formula (IB) wherein R1, R2, R3, R4, R5, and R6 are as defined herein for Formula (IA) or Formula (IB), or a tautomer, prodrug, solvate,or salt thereof; pharmaceutical compositions containing such compounds, and methods of modulating the glucocorticoid receptor function and methods of treating disease-states or conditions mediated by the glucocorticoid receptor function or characterized by inflammatory, allergic, or proliferative processes in a patient using these compounds.
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