发明公开
- 专利标题： USE OF INTERLEUKIN-19 TO TREAT CERVICAL CANCER
- 专利标题（中）： 白细胞介素19对治疗宫颈癌的用途
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申请号： EP03719611.0申请日： 2003-04-08
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公开(公告)号： EP1492560A2公开(公告)日： 2005-01-05
- 发明人: CHANDRASEKHER, Yasmin, A. , MCKERNAN, Patricia, A.
- 申请人： ZymoGenetics, Inc.
- 申请人地址： 1201 Eastlake Avenue East Seattle, WA 98102 US
- 专利权人： ZymoGenetics, Inc.
- 当前专利权人： ZymoGenetics, Inc.
- 当前专利权人地址： 1201 Eastlake Avenue East Seattle, WA 98102 US
- 代理机构： MacLean, Martin Robert
- 优先权： US371620P 20020410
- 国际公布： WO2003087307 20031023
- 主分类号： A61K38/19
- IPC分类号： A61K38/19 ; G01N33/53
摘要：
The present invention relates to the anti-cancer activity of IL-19 polypeptide molecules. IL-19 is a cytokine involved in inflammatory processes and human disease. The present invention includes Use of IL-19 for decreasing proliferation of cervical cancer cells, treating cervical cancer, amongst other uses disclosed. IL-19 polypeptides can be administered alone, or can be fused to cytotoxic moieties, and can be administered in conjunction with radiation or chemotherapeutic agents.
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