发明公开
- 专利标题： HEPATITIS C VIRUS ASSAY SYSTEMS
- 专利标题（中）： 丙肝病毒检测系统
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申请号： EP03721825申请日： 2003-04-11
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公开(公告)号： EP1499748A4公开(公告)日： 2005-10-12
- 发明人: FLORES OSVALDO A , GROBLER JAY , MURRAY EDWARD M , ZUCK PAUL D
- 申请人： MERCK & CO INC
- 专利权人： MERCK & CO INC
- 当前专利权人： MERCK & CO INC
- 优先权： US37284702 2002-04-16
- 主分类号： C07K14/02
- IPC分类号： C07K14/02 ; C12N15/86 ; C12Q1/34 ; C12Q1/68 ; C12Q1/70 ; G01N33/50 ; G01N33/576 ; C07H21/02 ; C07H21/04 ; C12N9/00 ; G01N33/53
摘要：
The present invention features assays employing a beta-lactamase reporter system, an HCV replicon enhanced cell, and/or a chimeric HCV replicon containing a 3' UTR based on the HCV-1a 3' UTR. These features can be employed alone or together, and are preferably combined together to measure HCV replicon activity and the affect of compounds on such activity
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