发明公开
EP1510555A1 8-(anilino)-1-naphthalenesulfonate analogs and their use in analyte detection assays
审中-公开
8-(苯胺基)-1-萘磺酸盐类似物及其在分析物检测分析中的用途
- 专利标题: 8-(anilino)-1-naphthalenesulfonate analogs and their use in analyte detection assays
- 专利标题(中): 8-(苯胺基)-1-萘磺酸盐类似物及其在分析物检测分析中的用途
-
申请号: EP04078255.9申请日: 2000-10-17
-
公开(公告)号: EP1510555A1公开(公告)日: 2005-03-02
- 发明人: Zheng, Xiaoling , Yu, Yeung Siu , Yani, Adva , Huang, Paing C.
- 申请人: Lifescan, Inc.
- 申请人地址: 1000 Gibraltar Drive Milpitas, California 95035-6312 US
- 专利权人: Lifescan, Inc.
- 当前专利权人: Lifescan, Inc.
- 当前专利权人地址: 1000 Gibraltar Drive Milpitas, California 95035-6312 US
- 代理机构: Mercer, Christopher Paul
- 优先权: US428296 19991027
- 主分类号: C09B27/00
- IPC分类号: C09B27/00 ; C07C309/47 ; C12Q1/28 ; C12Q1/54
摘要:
8-(anilino)-1-naphthalenesulfonate (ANS) analogs and methods for their use in analyte detection assays are provided. The subject ANS analogs are characterized by having at least one non-hydrogen substituent on their phenyl moiety and producing a reaction product with 3-methyl-benzothiazolinone hydrazone hydrochloride (MBTH) or an analog thereof, e.g. MBTHSB, that exhibits reduced drift. In certain preferred embodiments, the subject ANS analogs are described by formula (I) wherein: n is 1 to 5; and X is a substituent other than H. The subject ANS analogs find use in a variety of applications, particularly in analyte detection assays, such as glucose detection assays.
信息查询