发明公开
EP1515725A2 USE OF CYCLOTHIOCARBAMATE DERIVATIVES IN TREATMENT OF HORMONE-RELATED CONDITIONS
审中-公开
环十八烷酸酯衍生物在治疗激素相关病症中的应用
- 专利标题： USE OF CYCLOTHIOCARBAMATE DERIVATIVES IN TREATMENT OF HORMONE-RELATED CONDITIONS
- 专利标题（中）： 环十八烷酸酯衍生物在治疗激素相关病症中的应用
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申请号： EP03761263.7申请日： 2003-06-23
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公开(公告)号： EP1515725A2公开(公告)日： 2005-03-23
- 发明人: FENSOME, Andrew , GRUBB, Gary , HARRISON, Diane, Deborah , WINNEKER, Richard, Craig , ZHANG, Puwen , KERN, Jeffrey, Curtis , TEREFENKO, Eugene, Anthony
- 申请人： Wyeth
- 申请人地址： Five Giralda Farms Madison, New Jersey 07940 US
- 专利权人： Wyeth
- 当前专利权人： Wyeth
- 当前专利权人地址： Five Giralda Farms Madison, New Jersey 07940 US
- 代理机构： Wileman, David Francis, Dr.
- 优先权： US391871P 20020625
- 国际公布： WO2004000801 20031231
- 主分类号： A61K31/535
- IPC分类号： A61K31/535 ; A61K31/265 ; A61K31/16
摘要：
The present invention provides methods of inducing contraception which includes delivering to a female a composition containing a compound of formula I, formula II, or tautomers thereof, in a regimen which involves delivering one or more of a selective estrogen receptor modulator, wherein formula I is: (I) and wherein R1-R5 and Q1 are defined as described herein. Methods of providing hormone replacement therapy and for treating carcinomas, dysfunctional bleeding, uterine leiomyomata, endometriosis, and polycystic ovary syndrome is provided which includes delivering a compound of formula I or formula II and a selective estrogen receptor modulator are also described.
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