USE OF THIO-OXINDOLE DERIVATIVES IN TREATMENT OF HORMONE-RELATED CONDITIONS
    1.
    发明公开
    USE OF THIO-OXINDOLE DERIVATIVES IN TREATMENT OF HORMONE-RELATED CONDITIONS 审中-公开
    噻吨酮衍生物在治疗激素相关病症中的应用

    公开(公告)号:EP1531806A2

    公开(公告)日:2005-05-25

    申请号:EP03739264.4

    申请日:2003-06-23

    申请人: Wyeth

    IPC分类号: A61K31/40

    CPC分类号: A61K31/404 A61K45/06

    摘要: The present invention provides methods of inducing contraception which includes delivering to a female a composition containing a compound of formula (I), or tautomers thereof, in a regimen which involves delivering one or more of a selective estrogen receptor modulator, wherein formula (I) and wherein R1-R5 and Q1 are defined as described herein. Methods of providing hormone replacement therapy and for treating carcinomas, dysfunctional bleeding, uterine leiomyomata, endometriosis, and polycystic ovary syndrome is provided which includes delivering a compound of formula I and a selective estrogen receptor modulator are also described.

    摘要翻译: 本发明提供了诱导避孕的方法,其包括在包括递送一种或多种选择性雌激素受体调节剂的方案中向女性递送含有式(I)化合物或其互变异构体的组合物,其中式(I) 并且其中R 1 -R 5和Q 1如本文所述定义。 提供了提供激素替代疗法和用于治疗癌症,功能失调性出血,子宫平滑肌瘤,子宫内膜异位和多囊卵巢综合征的方法,其还包括递送式I化合物和选择性雌激素受体调节剂。

    USE OF CYCLOTHIOCARBAMATE DERIVATIVES IN TREATMENT OF HORMONE-RELATED CONDITIONS
    2.
    发明公开
    USE OF CYCLOTHIOCARBAMATE DERIVATIVES IN TREATMENT OF HORMONE-RELATED CONDITIONS 审中-公开
    环十八烷酸酯衍生物在治疗激素相关病症中的应用

    公开(公告)号:EP1515725A2

    公开(公告)日:2005-03-23

    申请号:EP03761263.7

    申请日:2003-06-23

    申请人: Wyeth

    摘要: The present invention provides methods of inducing contraception which includes delivering to a female a composition containing a compound of formula I, formula II, or tautomers thereof, in a regimen which involves delivering one or more of a selective estrogen receptor modulator, wherein formula I is: (I) and wherein R1-R5 and Q1 are defined as described herein. Methods of providing hormone replacement therapy and for treating carcinomas, dysfunctional bleeding, uterine leiomyomata, endometriosis, and polycystic ovary syndrome is provided which includes delivering a compound of formula I or formula II and a selective estrogen receptor modulator are also described.

    摘要翻译: 本发明提供诱导避孕的方法,其包括在包括递送一种或多种选择性雌激素受体调节剂的方案中向女性递送含有式I,式II或其互变异构体的化合物的组合物,其中式I是 :(I)并且其中R 1 -R 5和Q 1如本文所述定义。 还提供了提供激素替代疗法和用于治疗癌症,功能失调性出血,子宫平滑肌瘤,子宫内膜异位和多囊卵巢综合征的方法,其包括递送式I或式II化合物和选择性雌激素受体调节剂。