发明公开
EP1520587A1 ALLERGY VACCINE COMPOSITION, PRODUCTION METHOD THEREOF AND USE OF SAME IN ALLERGY TREATMENT
有权
过敏症疫苗组合物，工艺用于生产相同的，它们在治疗过敏
- 专利标题： ALLERGY VACCINE COMPOSITION, PRODUCTION METHOD THEREOF AND USE OF SAME IN ALLERGY TREATMENT
- 专利标题（中）： 过敏症疫苗组合物，工艺用于生产相同的，它们在治疗过敏
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申请号： EP03724819.2申请日： 2003-05-08
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公开(公告)号： EP1520587A1公开(公告)日： 2005-04-06
- 发明人: Lastre Gonzalez, Miriam de San Juan , Perez Martin, Oliver Germán , Labrada Rosado, Alexis , Bidot Martinez, Igor , Perez Lastre, Jorge Ernesto , Bracho Granada, Gustavo Rafael , Del Campo Alonso, Judith Monica , Perez Lastre, Dainerys Aleida , Facenda Ramos, Elisa , Zayas Vignier, Caridad , Rodriguez Martinez, Claudio , Sierra Gonzélez, Victoriano Gustavo
- 申请人： Instituto Finlay, Centro de Investigacion-Produccion de vacunas y sueros , Centro Nacional de Biopreparados
- 申请人地址： Ave 27 No 19805 e/198 y 202 La Coronela, La Lisa, Ciudad Habana 13500 CU
- 专利权人： Instituto Finlay, Centro de Investigacion-Produccion de vacunas y sueros,Centro Nacional de Biopreparados
- 当前专利权人： Instituto Finlay, Centro de Investigacion-Produccion de vacunas y sueros,Centro Nacional de Biopreparados
- 当前专利权人地址： Ave 27 No 19805 e/198 y 202 La Coronela, La Lisa, Ciudad Habana 13500 CU
- 代理机构： Winckels, J.H.F., Mr. Ir.
- 优先权： CU912002 20020508
- 国际公布： WO2003094964 20031120
- 主分类号： A61K39/39
- IPC分类号： A61K39/39 ; A61K39/35
摘要：
The present invention rebates to the field of Immunology, specifically with the branch of Immuno-Allergy and in particular with the use of adjuvant or carrier compounds, capable of modulating the immune response to allergens. The technical objective that is pursued is to obtain a pharmaceutical preparation of therapeutic or prophylactic use using bacterial proteoliposomes, which transform the allergic response Th2 and IgE when being applied in allergic individuals, toward a protector response Th1; as well as it is able to prevent the appearance and the development of allergies in individuals non-allergic yet. The vaccine composition consists of proteoliposomes derived from Gram-negative bacteria coupled to allergens and optionally contains other adjuvants or antigens. The method for its preparation and an immunization scheme of two doses are provided.
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