发明授权
EP1520587B1 ALLERGY VACCINE COMPOSITION, PRODUCTION METHOD THEREOF AND USE OF SAME IN ALLERGY TREATMENT
有权
过敏症疫苗组合物，工艺用于生产相同的，它们在治疗过敏
- 专利标题： ALLERGY VACCINE COMPOSITION, PRODUCTION METHOD THEREOF AND USE OF SAME IN ALLERGY TREATMENT
- 专利标题（中）： 过敏症疫苗组合物，工艺用于生产相同的，它们在治疗过敏
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申请号： EP03724819.2申请日： 2003-05-08
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公开(公告)号： EP1520587B1公开(公告)日： 2011-06-29
- 发明人: Lastre González, Miriam de San Juan , Pérez Martín, Oliver Germán , Labrada Rosado, Alexis , Bidot Martínez, Igor , Pérez Lastre, Jorge Ernesto , Bracho Granada, Gustavo Rafael , Del Campo Alonso, Judith Mónica , Pérez Lastre, Dainerys Aleida , Facenda Ramos, Elisa , Zayas Vignier, Caridad , Rodríguez Martínez, Claudio , Sierra Gonzàlez, Victoriano Gustavo
- 申请人： Instituto Finlay, Centro de Investigacion-Produccion de vacunas y sueros , CENTRO NACIONAL DE BIOPREPARADOS
- 申请人地址： Ave 27 No 19805 e/198 y 202 La Coronela, La Lisa, Ciudad Habana 13500 CU
- 专利权人： Instituto Finlay, Centro de Investigacion-Produccion de vacunas y sueros,CENTRO NACIONAL DE BIOPREPARADOS
- 当前专利权人： Instituto Finlay, Centro de Investigacion-Produccion de vacunas y sueros,CENTRO NACIONAL DE BIOPREPARADOS
- 当前专利权人地址： Ave 27 No 19805 e/198 y 202 La Coronela, La Lisa, Ciudad Habana 13500 CU
- 代理机构： Winckels, Johannes Hubertus F.
- 优先权： CU912002 20020508
- 国际公布： WO2003094964 20031120
- 主分类号： A61K39/39
- IPC分类号： A61K39/39 ; A61K39/35
摘要：
The invention relates to the field of immunology, immunoallergy and, in particular, the use of adjuvants or carriers in order to modulate the immunological response to allergens. The technical objective of the invention is: to produce a therapeutic or prophylactic pharmaceutical preparation using bacterial proteoliposomes, which, when applied to allergic individuals, transforms the Th2- and IgE-dependent allergic response into a protective Th1 response; and to prevent the appearance and development of allergies in not-yet allergic individuals. The vaccine composition consists of proteoliposomes of gram-negative bacteria coupled with allergens and, optionally, other antigens or adjuvants. The invention also relates to the method of producing the inventive vaccine composition and to the two-dose schedule for immunisation with said vaccine composition.
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