发明公开
- 专利标题: BICYCLIC UNSATURATED TERTIARY AMINE COMPOUND
- 专利标题(中): 双环,饱和叔胺化合物
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申请号: EP03765317申请日: 2003-07-17
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公开(公告)号: EP1541571A4公开(公告)日: 2008-12-03
- 发明人: KIMURA TOMIO , OHKAWA NOBUYUKI , AOKI KAZUMASA , NAKAO AKIRA , NAGASAKI TAKAYOSHI
- 申请人: SANKYO CO
- 专利权人: SANKYO CO
- 当前专利权人: SANKYO CO
- 优先权: JP2002211836 2002-07-19
- 主分类号: A61P1/00
- IPC分类号: A61P1/00 ; A61P1/16 ; A61P3/10 ; A61P9/00 ; A61P9/10 ; A61P11/06 ; A61P13/12 ; A61P17/06 ; A61P19/02 ; A61P19/10 ; A61P25/04 ; A61P25/28 ; A61P29/00 ; A61P31/12 ; A61P35/00 ; A61P37/02 ; A61P37/08 ; A61P43/00 ; C07D471/04 ; A61K31/444
摘要:
A bicyclic unsaturated tertiary amine compound which can inhibit the production of inflammatory cytokine. It is a compound represented by the following general formula (I), pharmacologically acceptable salt thereof, pharmacologically acceptable ester thereof, or pharmacologically acceptable other derivative thereof: (I) wherein A represents pyrrole or pyrazole; R1 represents optionally substituted aryl or heteroaryl; R2 represents optionally substituted heteroaryl; and R3 represents indolizine.
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