发明授权
EP1543051B1 BUFFER POLYMERS, CO-IMMOBILE BUFFER AND ENZYME POLYMERS AND METHODS OF SYNTHESIS THEREOF
有权
与IMMBOBILISIERTEM缓冲器和固定化酶和合成方法THEREFOR BUFFER聚合物聚合物
- 专利标题： BUFFER POLYMERS, CO-IMMOBILE BUFFER AND ENZYME POLYMERS AND METHODS OF SYNTHESIS THEREOF
- 专利标题（中）： 与IMMBOBILISIERTEM缓冲器和固定化酶和合成方法THEREFOR BUFFER聚合物聚合物
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申请号： EP03784929.6申请日： 2003-08-06
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公开(公告)号： EP1543051B1公开(公告)日： 2011-11-02
- 发明人: LEJEUNE, Keith, E. , ALLINSON, Bryan
- 申请人： Agentase, LLC
- 申请人地址： 3636 Boulevard of the Allies Pittsburgh, PA 15213 US
- 专利权人： Agentase, LLC
- 当前专利权人： Agentase, LLC
- 当前专利权人地址： 3636 Boulevard of the Allies Pittsburgh, PA 15213 US
- 代理机构： O'Connell, Maura
- 优先权： US215337 20020808
- 国际公布： WO2004014974 20040219
- 主分类号： C12N11/08
- IPC分类号： C12N11/08 ; C08G18/10 ; C08G18/64
摘要：
A polyurethane polymer includes at least one buffer selected to adjust pH to a pH within a desired range. The buffer compound is immobilized within the polymer, and the polymer has a buffer capacity in excess of 3 micromoles of acid or base per gram polymer. A polymer includes at least one enzyme that is selected to catalyze a reaction of a substance. The enzyme is immobilized within the polymer. The polymer also includes at least one buffer selected to adjust the pH in the vicinity of the enzyme to a pH within a desired range. The buffer compound is also immobilized within the polymer. The polymer preferably has enzyme activity and a buffer capacity in excess of 3 micromoles acids or base per gram polymer. In one embodiment, each of the enzymes(s) and the buffer(s) are covalently bonded to the polymer.
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