发明公开
EP1546203A2 ALPHA-FETOPROTEIN IMMU31 ANTIBODIES AND FUSION PROTEINS AND METHODS OF USE THEREOF
有权
甲胎蛋白IMMU31抗体和融合蛋白和申请流程。
- 专利标题： ALPHA-FETOPROTEIN IMMU31 ANTIBODIES AND FUSION PROTEINS AND METHODS OF USE THEREOF
- 专利标题（中）： 甲胎蛋白IMMU31抗体和融合蛋白和申请流程。
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申请号： EP03766456.2申请日： 2003-08-01
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公开(公告)号： EP1546203A2公开(公告)日： 2005-06-29
- 发明人: HANSEN, Hans , QU, Zhengxing , GOLDENBERG, David, M.
- 申请人： Immunomedics, Inc.
- 申请人地址： 300 American Road Morris Plains,New Jersey 07950 US
- 专利权人： Immunomedics, Inc.
- 当前专利权人： Immunomedics, Inc.
- 当前专利权人地址： 300 American Road Morris Plains,New Jersey 07950 US
- 代理机构： Soames, Candida Jane
- 优先权： US399707P 20020801
- 国际公布： WO2004013180 20040212
- 主分类号： C07K16/18
- IPC分类号： C07K16/18 ; C07K16/46 ; A61K51/10 ; A61K47/48 ; A61K39/395 ; G01N33/573 ; G01N33/574 ; C12N15/13 ; C12N15/62 ; C12N15/79 ; C12N5/10 ; A61P35/00 ; C12Q1/68
摘要：
The present invention provides humanized, chimeric and human anti-alpha-fetoprotein antibodies, fusion proteins, and fragments thereof. The antibodies, fusion proteins, and fragments thereof, as well as combinations with other suitable antibodies, are useful for the treatment and diagnosis of hepatocellular carcinoma, hepatoblastoma, germ cell tumors carcinoma and other AFP-producing tumors.
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