发明公开
- 专利标题: SUBSTITUTED INDOLES AND THEIR USE AS HCV INHIBITORS
- 专利标题(中): 取代吲哚及其作为HCV抑制剂的用途
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申请号: EP03781338.3申请日: 2003-10-15
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公开(公告)号: EP1554271A1公开(公告)日: 2005-07-20
- 发明人: SINGH, Rajinder , DARWISH, Ihab, S. , KOLLURI, Rao S. S. , THOTA, Sambaiah , LU, Henry, H.
- 申请人: Rigel Pharmaceuticals, Inc.
- 申请人地址: 240 E. Grand Avenue South San Francisco, CA 94080 US
- 专利权人: Rigel Pharmaceuticals, Inc.
- 当前专利权人: Rigel Pharmaceuticals, Inc.
- 当前专利权人地址: 240 E. Grand Avenue South San Francisco, CA 94080 US
- 代理机构: Mallalieu, Catherine Louise
- 优先权: US419012P 20021015
- 国际公布: WO2004035571 20040429
- 主分类号: C07D409/12
- IPC分类号: C07D409/12 ; C07D401/12 ; C07D407/12 ; C07D417/12 ; C07D209/08 ; A61K31/404
摘要:
The present invention comprises indole-derivatives that are inhibitors of HCV. Composition comprising the compounds in combination with a pharmaceutically acceptable carrier are also disclosed, as are methods of using the compounds and compositions to inhibit HCV infection of a cell, particular in the form of treating HCV infection in a mammal.
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