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公开(公告)号：EP3047001A1
公开(公告)日：2016-07-27
申请号：EP14780714.3
申请日：2014-09-19
IPC分类号： C10M169/04 , C10N40/25
CPC分类号： C10M169/04 , C10M129/76 , C10M133/12 , C10M2203/1025 , C10M2207/026 , C10M2207/028 , C10M2215/064 , C10M2215/28 , C10M2219/022 , C10M2219/046 , C10N2210/02 , C10N2240/104 , C10N2220/022
摘要： The invention is directed to a method for reducing low speed pre-ignition events in a spark-ignited direct injection internal combustion engine by supplying to the sump a lubricant composition which contains an oil of lubricating viscosity and an ashless antioxidant. The ashless antioxidant may be selected from phenolic compounds, aryl amine compounds, and sulfurized olefins, especially 2,6-hindered phenols and diarylamine compounds.
摘要翻译： 本发明涉及一种用于减少火花点燃直接喷射内燃机中的低速早燃事件的方法，其通过向储槽供应含有润滑粘度的油和无灰抗氧化剂的润滑剂组合物。 无灰抗氧化剂可以选自酚化合物，芳基胺化合物和硫化烯烃，特别是2,6-受阻酚和二芳基胺化合物。
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公开(公告)号：EP3039104A1
公开(公告)日：2016-07-06
申请号：EP14790398.3
申请日：2014-09-30
IPC分类号： C10M133/56 , C10M133/16 , C10N30/04 , C10N30/06 , C10N40/04 , C10N40/25
CPC分类号： C10M133/58 , C10M133/16 , C10M133/56 , C10M2215/086 , C10M2215/28 , C10M2215/30 , C10N2040/25 , C10N2220/021 , C10N2230/04 , C10N2230/06 , C10N2240/04 , C10N2240/10 , C10N2240/104
摘要： This invention relates to a method of lubricating an internal combustion engine comprising at least one of a crankcase, a gear and a wet-clutch, said method comprising supplying to said crankcase, gear, and wet-clutch a lubricating composition containing: (a) an oil of lubricating viscosity; and (b) a friction modifying additive which is the reaction product of a hydrocarbyl-substituted succinic anhydride and an acid functionalized amine compound.
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3.发明公开LUBRICANT COMPRISING A MIXTURE OF AN OLEFIN-ESTER COPOLYMER WITH AN ETHYLENE ALPHA-OLEFIN COPOLYMER 有权EMIEM ELEEMO ELEME ELEEMO-ESTER共聚物在EINEM ETHYLENE ALPHA-OLEFIN COPOLYMER
公开(公告)号：EP2898051A1
公开(公告)日：2015-07-29
申请号：EP13770761.8
申请日：2013-09-17
发明人： KNAPTON, Daniel J.
IPC分类号： C10M157/00 , C10M157/04
CPC分类号： C10M169/047 , C10M157/00 , C10M157/04 , C10M2205/022 , C10M2205/028 , C10M2205/0285 , C10M2217/06 , C10N2220/021 , C10N2230/02 , C10N2230/06 , C10N2230/42 , C10N2240/04 , C10N2240/046 , C10M2209/08 , C10M2209/086
摘要： A lubricant composition comprising an oil of lubricating viscosity having a kinematic viscosity at 100° C of less than 15 mm
2 /s; and an esterified copolymer with a backbone comprising units derived from (i) an α-olefin monomer of at least 6 carbon atoms and (ii) an ethylenically unsaturated carboxylic acid or derivative thereof, optionally containing nitrogen functionality; and an ethylene α-olefin copolymer comprising greater than 5 weight percent ethylene monomer units, exhibits good operating efficiency when used to lubricate a mechanical device.摘要翻译： 一种润滑剂组合物，其包含润滑粘度在100℃下的运动粘度小于15mm 2 / s的油; 和包含衍生自（i）至少6个碳原子的α-烯烃单体和（ii）烯键式不饱和羧酸或其衍生物，任选地含有氮官能团的单元的骨架的酯化共聚物; 和包含大于5重量％乙烯单体单元的乙烯α-烯烃共聚物在用于润滑机械装置时表现出良好的操作效率。
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公开(公告)号：EP1825005B1
公开(公告)日：2015-07-15
申请号：EP05852182.4
申请日：2005-11-23
IPC分类号： A61K39/395 , G01N33/53 , G01N33/574 , C07K16/30 , C07K16/28 , G01N33/86
CPC分类号： C07K16/30 , C07K14/705 , C07K16/2863 , G01N33/57426 , G01N33/86 , G01N2333/71
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5.发明授权
公开(公告)号：EP1765085B1
公开(公告)日：2015-07-08
申请号：EP05782697.6
申请日：2005-05-17
IPC分类号： A01N63/00
CPC分类号： C12N5/0611 , A61B17/43 , A61K35/14 , A61K35/28 , A61K2035/124 , C12N5/0609 , C12N5/0634 , C12N2506/11 , C12P21/06
摘要： The present invention relates to methods of isolation of female germline stem cells and their progenitors.
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公开(公告)号：EP2885387A1
公开(公告)日：2015-06-24
申请号：EP13751060.8
申请日：2013-08-14
发明人： BARTON, William R.S.
IPC分类号： C10M145/12 , C10M145/16 , C10M169/04 , C10N20/02 , C10N30/02 , C10N40/04 , C10N40/08 , C10N40/20 , C10N40/25
CPC分类号： C10M107/28 , C10M145/12 , C10M145/16 , C10M2203/108 , C10M2205/02 , C10M2205/0225 , C10M2205/028 , C10M2205/0285 , C10M2205/04 , C10M2209/082 , C10M2209/084 , C10M2209/086 , C10N2220/021 , C10N2220/022 , C10N2220/033 , C10N2230/02 , C10N2230/54 , C10N2230/68 , C10N2240/04 , C10N2240/042 , C10N2240/044 , C10N2240/08 , C10N2240/10 , C10N2240/40 , C10N2260/06 , C10N2260/09 , C10M2205/0245 , C10M2209/0845 , C10M2209/0863
摘要： A lubricating composition includes an (A) esterified copolymer comprising units (A1) derived from a vinyl monomer and units (A2) derived from a carboxylic acid monomer, the vinyl monomer comprising a vinyl aliphatic monomer, the carboxylic acid monomer comprising an ethylenically unsaturated carboxylic acid or derivative thereof, esterified with a primary alcohol; and (B) an oil of lubricating viscosity. The lubricating composition can provide a lubricant with at least one (or at least two, or all) of acceptable or improved HTHS, KV, shear stability, acceptable or improved viscosity index control, and acceptable or improved low temperature viscosity.
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公开(公告)号：EP2885328A1
公开(公告)日：2015-06-24
申请号：EP13710725.6
申请日：2013-03-05
IPC分类号： C08F220/18 , C08F222/10 , C10M145/14 , C08F297/00
CPC分类号： C08F265/06 , C08F220/18 , C08F222/1006 , C08F293/005 , C08F2438/03 , C10M145/14 , C10M2209/084 , C10N2220/021 , C10N2220/029 , C10N2240/04 , C10N2240/08 , C10N2240/10
摘要： The present invention relates to star polymer having a core made up of a crosslinked network of polymers derived from a mixture of one or more multi-functional monomers and one or more mono-functional monomers and where the star polymer has arms made of polymers derived from a mixture of one or more mono-functional monomers, where the star contains at least three arms bonded to the core. The invention further relates to lubricating compositions containing an oil of lubricating viscosity and the described star polymers as well as methods of lubricating a mechanical device with the described lubricating compositions.
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公开(公告)号：EP1877526B1
公开(公告)日：2015-05-13
申请号：EP06739734.9
申请日：2006-03-27
发明人： BROWN, Jason R. , ADAMS, Paul E. , CARRICK, Virginia A. , DOHNER, Brent R. , ABRAHAM, William D. , VILARDO, Jonathan S. , LANGE, Richard M. , MOSIER, Patrick E.
IPC分类号： C10M163/00 , C10M159/12
CPC分类号： C10M169/04 , C10M159/12 , C10M159/18 , C10M163/00 , C10M2201/062 , C10M2205/04 , C10M2207/021 , C10M2207/026 , C10M2207/028 , C10M2207/10 , C10M2207/262 , C10M2207/289 , C10M2209/086 , C10M2215/064 , C10M2215/08 , C10M2215/28 , C10M2219/022 , C10M2219/046 , C10M2223/042 , C10M2223/045 , C10M2227/065 , C10N2210/02 , C10N2210/04 , C10N2220/082 , C10N2230/00 , C10N2230/04 , C10N2230/10 , C10N2240/10 , C10N2240/102 , C10N2260/00 , C10M2205/024 , C10M2205/06
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9.发明授权PYRIDAZINE COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISEASES 有权PYRIDAZINVERBINDUNGEN ZUR BEHANDLUNG VONENTZÜNDLICHENERKRANKUNGEN
公开(公告)号：EP2592075B1
公开(公告)日：2015-04-29
申请号：EP13154085.8
申请日：2005-11-02
申请人： Northwestern University , Université de Strasbourg , Centre National de la Recherche Scientifique
发明人： Watterson, D. Martin , Van Eldik, Linda , Haiech, Jacques , Hibert, Marcel , Bouguignon, Jean-Jacques , Velentza, Anastasia , Hu, Wenhui , Zasadzki, Magdalena
IPC分类号： C07D401/04 , A61K31/502 , A61P25/00 , A61P37/00
CPC分类号： C07D401/12 , A61K31/502 , C07D237/20 , C07D237/24 , C07D237/34 , C07D401/04 , C07D403/12 , C07D413/12 , C07D413/14 , C07D487/04 , C07H19/16
摘要： The invention relates to novel chemical compounds, compositions and methods of making and using the same. In particular, the invention provides pyridazine compounds and/or related heterocyclic derivatives, compositions comprising the same, and methods of making and using pyridazine compounds and/or related heterocyclic derivatives and compositions comprising the same, for modulation of cellular pathways (e.g., signal transduction pathways), for treatment or prevention of inflammatory diseases (e.g., Alzheimer's disease), for research, drug screening, and therapeutic applications. Compounds of Formula Ia or Ib or wherein R is a substituted amino group, R 2 is an unsaturated 5 to 6-membered heteromonocyclic group containing 1 to 4 nitrogen atoms, R 3 , R 4 , R 5 , and R 6 are hydrogen, and R 7 is absent; or a pharmaceutically acceptable salt thereof.
摘要翻译： 本发明涉及新颖的化合物，组合物和制备和使用它们的方法。 特别地，本发明提供哒嗪化合物和/或相关杂环衍生物，包含其的组合物，以及制备和使用哒嗪化合物和/或相关杂环衍生物的方法及其组合物，用于调节细胞途径（例如，信号转导 途径），用于治疗或预防炎性疾病（如阿尔茨海默病），用于研究，药物筛选和治疗应用。 式Ia或Ib的化合物或其中R是取代的氨基，R 2是含有1至4个氮原子的不饱和5至6元杂单环基团，R 3，R 4，R 5和R 6是氢，和 R 7不存在 或其药学上可接受的盐。
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公开(公告)号：EP2049200B1
公开(公告)日：2015-04-29
申请号：EP07870696.7
申请日：2007-05-21
申请人： MethylGene Inc.
发明人： DININNO, Frank , HAMMOND, Milton L. , DYKSTRA, Kevin , KIM, Seongkon , TAN, Qiang , YOUNG, Katherine , HERMES, Jeffrey Donald , CHEN, Helen , RAEPPEL, Stephane , MANNION, Michael , GAUDETTE, Frederic , VAISBURG, Arkadii , RAHL, Jubrail , GEORGOPAPADAKOU, Nafsika , ZHOU, Nancy Z.
IPC分类号： A61P31/04 , C07F9/6539 , C07F9/6541 , C07F9/6553 , C07F9/6558 , C07F9/6561 , A61K31/67 , A61K31/675
CPC分类号： C07F9/655354 , C07F9/65395 , C07F9/6541 , C07F9/6553 , C07F9/6558 , C07F9/6561
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