发明公开
EP1558612A1 DERIVES D'IMIDAZOPYRIDINE, LEUR PROCEDE DE PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES QUI LES CONTIENNENT
有权
IMIDAZOPYRIN衍生物,工艺用于生产和装有药剂一起住区
- 专利标题: DERIVES D'IMIDAZOPYRIDINE, LEUR PROCEDE DE PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES QUI LES CONTIENNENT
- 专利标题(英): Imidazopyridine derivatives, preparation method and pharmaceutical compositions containing same
- 专利标题(中): IMIDAZOPYRIN衍生物,工艺用于生产和装有药剂一起住区
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申请号: EP03767889.3申请日: 2003-11-04
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公开(公告)号: EP1558612A1公开(公告)日: 2005-08-03
- 发明人: RAULT, Sylvain , LANCELOT, Jean-Charles , KOPP, Marina , CAIGNARD, Daniel-Henri , PFEIFFER, Bruno , RENARD, Pierre , BIZOT-ESPIARD, Jean-Guy
- 申请人: LES LABORATOIRES SERVIER
- 申请人地址: 12, place de la Défense 92415 Courbevoie Cédex FR
- 专利权人: LES LABORATOIRES SERVIER
- 当前专利权人: LES LABORATOIRES SERVIER
- 当前专利权人地址: 12, place de la Défense 92415 Courbevoie Cédex FR
- 优先权: FR0213802 20021105
- 国际公布: WO2004043957 20040527
- 主分类号: C07D471/04
- IPC分类号: C07D471/04 ; A61K31/44
摘要:
The invention concerns compounds of formula (I), wherein R1 represents a hydrogen, halogen atom, an alkyl, polyhalogenoalkyl, cyano, nitro, hydroxycarbonyl, alkoxycarbonyl, aminocarbonyl, alkylaminocarbonyl, or dialkylaminocarbonyl group; R2 represents a hydrogen atom, an alkyl, aryl group optionally substituted, heteroaryl optionally substituted or a R20-C(X) group, R20 representing an alkyl, alkoxy, amino, alkylamino, dialkylamino, aryl optionally substituted or heteroaryl group; X represents an oxygen atom, a sulphur atom, or a NR21 group, wherein R21 represents a hydrogen atom or an alkyl group; R3 represents a hydrogen atom or an alkyl group; n represents an integer between 1 and 6 inclusively, R1 has the following meanings (A); their enantiomers, diastereoisomers, as well as their addition salt to a pharmaceutically acceptable acid or base. The invention is useful for preparing medicines.
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