发明公开
EP1567487A2 OPEN CHAIN PROLYL UREA-RELATED MODULATORS OF ANDROGEN RECEPTOR FUNCTION
审中-公开
开链雄激素受体相关调节剂对雄激素受体功能的影响
- 专利标题： OPEN CHAIN PROLYL UREA-RELATED MODULATORS OF ANDROGEN RECEPTOR FUNCTION
- 专利标题（中）： 开链雄激素受体相关调节剂对雄激素受体功能的影响
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申请号： EP03808410.9申请日： 2003-11-13
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公开(公告)号： EP1567487A2公开(公告)日： 2005-08-31
- 发明人: HAMANN, Lawrence, G. , AUGERI, David, J. , MANFREDI, Mark, C.
- 申请人： Bristol-Myers Squibb Company
- 申请人地址： P.O. Box 4000, Route 206 and Provinceline Road Princeton, NJ 08543-4000 US
- 专利权人： Bristol-Myers Squibb Company
- 当前专利权人： Bristol-Myers Squibb Company
- 当前专利权人地址： P.O. Box 4000, Route 206 and Provinceline Road Princeton, NJ 08543-4000 US
- 代理机构： Beacham, Annabel Rose
- 优先权： US426694P 20021115
- 国际公布： WO2004045518 20040603
- 主分类号： C07D207/04
- IPC分类号： C07D207/04 ; C07D211/06 ; A61K31/445 ; A61K31/401 ; A61P3/04 ; A61P3/10 ; A61P9/12 ; A61P25/22 ; A61P25/24
摘要：
The invention provides for a pharmaceutical composition capable of modulating the androgen receptor comprising a compound of formula (I), wherein R1, R2, R3, X, Y, Z and G are as described herein. Further provided are methods of using such compounds for the treatment of nuclear hormone receptor-associated conditions, such as age related diseases, for example sarcopenia, and also provided are pharmaceutical compositions containing such compounds.
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