发明公开
EP1571225A1 Diagnosis of a disease and monitoring of therapy using the AC133 gene
审中-公开
诊断von Krankheiten undÜberwachungeiner Therapie unter Verwendung des AC133 Gens
- 专利标题： Diagnosis of a disease and monitoring of therapy using the AC133 gene
- 专利标题（中）： 诊断von Krankheiten undÜberwachungeiner Therapie unter Verwendung des AC133 Gens
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申请号： EP04075686.8申请日： 2004-03-02
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公开(公告)号： EP1571225A1公开(公告)日： 2005-09-07
- 发明人: Penning, Maarten Tjerk , Beerepoot, Laurens Victor , van den Broek, Sebastiaan Johannes Jacobus , Mehra, Niven , Voest, Emile Eugene
- 申请人： PrimaGen Holding B.V. , UMC Utrecht Holding B.V.
- 申请人地址： Meibergdreef 59 1105 BA Amsterdam NL
- 专利权人： PrimaGen Holding B.V.,UMC Utrecht Holding B.V.
- 当前专利权人： PrimaGen Holding B.V.,UMC Utrecht Holding B.V.
- 当前专利权人地址： Meibergdreef 59 1105 BA Amsterdam NL
- 代理机构： Winckels, Johannes Hubertus F.
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68
摘要：
The invention provides a method for typing a sample of an individual suffering from, or at risk of suffering from, a disease and a method for monitoring treatment of an individual suffering from a disease comprising determining whether a sample from said individual comprises an expression product of AC133 in an amount that is indicative for said disease or for the treatment thereof. Said amount is preferably quantified and compared with a reference value. In one aspect said amount is compared with an amount of said expression product present in a sample that was obtained from said individual before said treatment. A use of a nucleic acid molecule comprising at least part of a sequence of AC133 or an analogue thereof for monitoring a treatment of an individual suffering from a disease is also provided, as well as a diagnostic kit comprising such nucleic acid molecule.
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