发明授权
- 专利标题: THERAPEUTIC HUMAN ANTI-IL-1R1 MONOCLONAL ANTIBODY
- 专利标题(中): 治疗性人单克隆抗IL-1R1抗体
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申请号: EP03752058.2申请日: 2003-09-05
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公开(公告)号: EP1572946B1公开(公告)日: 2012-03-14
- 发明人: VARNUM, Brian , VEZINA, Chris , WITTE, Alison , QIAN, Xueming , MARTIN, Frank , HUANG, Haichun , ELLIOTT, Gary
- 申请人: Amgen, Inc. , Medarex, Inc.
- 申请人地址: One Amgen Center Drive Thousand Oaks, CA 91320-1799 US
- 专利权人: Amgen, Inc.,Medarex, Inc.
- 当前专利权人: Amgen, Inc.,Medarex, Inc.
- 当前专利权人地址: One Amgen Center Drive Thousand Oaks, CA 91320-1799 US
- 代理机构: Grünecker, Kinkeldey, Stockmair & Schwanhäusser
- 优先权: US408719P 20020906
- 国际公布: WO2004022718 20040318
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; C07K16/28
摘要:
Antibodies that interact with interleukin-1 receptor type 1 (IL-1R1) are described. Methods of treating IL-1 mediated diseases by administering a pharmaceutically effective amount of antibodies to IL-1R1 are described. Methods of detecting the amount of IL-1R1 in a sample using antibodies to IL-1R1 are described.
公开/授权文献
- EP1572946A2 THERAPEUTIC HUMAN ANTI-IL-1R1 MONOCLONAL ANTIBODY 公开/授权日:2005-09-14
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